Discovery and Engineering of the Cocaine Biosynthetic Pathway.
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DOI: 10.1021/jacs.2c09091
Abstract: Cocaine, the archetypal tropane alkaloid from the plant genus Erythroxylum, has recently been used clinically as a topical anesthesia of the mucous membranes. Despite this, the key biosynthetic step of the requisite tropane skeleton (methylecgonone)… read more here.
Keywords: engineering cocaine; pathway; tropane; cocaine ... See more keywords