Semiconductor photocatalysis to engineering deuterated N-alkyl pharmaceuticals enabled by synergistic activation of water and alkanols
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DOI: 10.1038/s41467-020-18458-w
Abstract: Precisely controlled deuterium labeling at specific sites of N-alkyl drugs is crucial in drug-development as over 50% of the top-selling drugs contain N-alkyl groups, in which it is very challenging to selectively replace protons with… read more here.
Keywords: deuterated alkyl; water; semiconductor; photocatalysis engineering ... See more keywords