Rational engineering in Escherichia coli for high‐titer production of baicalein based on genome‐scale target identification
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DOI: 10.1002/bit.28087
Abstract: Baicalein is a bioactive flavonoid isolated from the traditional Chinese medicinal plant, Scutellaria baicalensis Georgi. Microbial synthesis of flavonoids has been intensively developed owing to the eco‐friendly nature of the process. However, the titer of… read more here.
Keywords: rational engineering; engineering escherichia; escherichia coli; identification ... See more keywords
Metabolic engineering of Escherichia coli for the production of glyoxylate from xylose
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2017.11.002
Abstract: Abstract Glyoxylate is an important chemical building block which is currently produced by chemical or electrochemical oxidation methods We herein described the achievement of microbial glyoxylate production from renewable biomass by metabolic engineering of Escherichia… read more here.
Keywords: production; metabolic engineering; escherichia coli; engineering escherichia ... See more keywords
Combinatorial metabolic engineering of Escherichia coli for de novo production of 2'-fucosyllactose.
Sign Up to like & getrecommendations! Published in 2022 at "Bioresource technology"
DOI: 10.1016/j.biortech.2022.126949
Abstract: 2'-Fucosyllactose (2'-FL) is a kind of fucosylated lactose of human milk oligosaccharides (HMOs). In this work, Escherichia coli MG1655 was metabolically engineered to increase 2'-FL production. The 2'-FL titer was raised from 0.0118 to 0.8062… read more here.
Keywords: coli novo; engineering escherichia; combinatorial metabolic; escherichia coli ... See more keywords
Engineering Escherichia coli to bind to cyanobacteria.
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DOI: 10.1016/j.jbiosc.2016.09.010
Abstract: We engineered Escherichia coli cells to bind to cyanobacteria by heterologously producing and displaying lectins of the target cyanobacteria on their surface. To prove the efficacy of our approach, we tested this design on Microcystis… read more here.
Keywords: coli cells; escherichia coli; coli bind; engineering escherichia ... See more keywords
Metabolic Engineering of Escherichia coli for High-Level Production of Salicin
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DOI: 10.1021/acsomega.2c03347
Abstract: Salicin is a notable phenolic glycoside derived from plants including Salix and Populus genus and has multiple biological activities such as anti-inflammatory and antiarthritic, anticancer, and antiaging effects. In this work, we engineered production of… read more here.
Keywords: engineering escherichia; metabolic engineering; escherichia coli; production ... See more keywords
Metabolic engineering of Escherichia coli for the production of isoprenoids.
Sign Up to like & getrecommendations! Published in 2018 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fny079
Abstract: Metabolic engineering is the practice of using directed genetic manipulations to rewire cellular metabolism primarily with the aim to transform the organism into a single-celled chemical factory. Using biological processes, we can produce more complex… read more here.
Keywords: engineering; production; metabolic engineering; escherichia coli ... See more keywords