Rational engineering in Escherichia coli for high‐titer production of baicalein based on genome‐scale target identification
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28087
Abstract: Baicalein is a bioactive flavonoid isolated from the traditional Chinese medicinal plant, Scutellaria baicalensis Georgi. Microbial synthesis of flavonoids has been intensively developed owing to the eco‐friendly nature of the process. However, the titer of… read more here.
Keywords: rational engineering; engineering escherichia; escherichia coli; identification ... See more keywords
Metabolic engineering of Escherichia coli for the production of glyoxylate from xylose
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2017.11.002
Abstract: Abstract Glyoxylate is an important chemical building block which is currently produced by chemical or electrochemical oxidation methods We herein described the achievement of microbial glyoxylate production from renewable biomass by metabolic engineering of Escherichia… read more here.
Keywords: production; metabolic engineering; escherichia coli; engineering escherichia ... See more keywords
Combinatorial metabolic engineering of Escherichia coli for de novo production of 2'-fucosyllactose.
Sign Up to like & getrecommendations! Published in 2022 at "Bioresource technology"
DOI: 10.1016/j.biortech.2022.126949
Abstract: 2'-Fucosyllactose (2'-FL) is a kind of fucosylated lactose of human milk oligosaccharides (HMOs). In this work, Escherichia coli MG1655 was metabolically engineered to increase 2'-FL production. The 2'-FL titer was raised from 0.0118 to 0.8062… read more here.
Keywords: coli novo; engineering escherichia; combinatorial metabolic; escherichia coli ... See more keywords
Engineering Escherichia coli to bind to cyanobacteria.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2016.09.010
Abstract: We engineered Escherichia coli cells to bind to cyanobacteria by heterologously producing and displaying lectins of the target cyanobacteria on their surface. To prove the efficacy of our approach, we tested this design on Microcystis… read more here.
Keywords: coli cells; escherichia coli; coli bind; engineering escherichia ... See more keywords
Engineering Escherichia coli for l-Threonine Hyperproduction Based on Multidimensional Optimization Strategies.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c07607
Abstract: Exploring effective remodeling strategies to further improve the productivity of high-yield strains is the goal of biomanufacturing. However, the lack of insight into host-specific metabolic networks prevents timely identification of useful engineering targets. Here, multidimensional… read more here.
Keywords: escherichia coli; threonine; coli threonine; engineering ... See more keywords
Combinatorial Metabolic Engineering of Escherichia coli MG1655 Enables Efficient Biosynthesis of Vitamin B6.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c03677
Abstract: Pyridoxine (PN) is the most important commercial form of vitamin B6. Currently, PN is chemically synthesized using toxic chemicals, causing environmental pollution. Microbial production of vitamin B6 offers a more sustainable alternative, but its low… read more here.
Keywords: combinatorial metabolic; vitamin; engineering escherichia; metabolic engineering ... See more keywords
Metabolic Engineering of Escherichia coli for High-Level Production of Salicin
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DOI: 10.1021/acsomega.2c03347
Abstract: Salicin is a notable phenolic glycoside derived from plants including Salix and Populus genus and has multiple biological activities such as anti-inflammatory and antiarthritic, anticancer, and antiaging effects. In this work, we engineered production of… read more here.
Keywords: engineering escherichia; metabolic engineering; escherichia coli; production ... See more keywords
Metabolic engineering of Escherichia coli for the production of isoprenoids.
Sign Up to like & getrecommendations! Published in 2018 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fny079
Abstract: Metabolic engineering is the practice of using directed genetic manipulations to rewire cellular metabolism primarily with the aim to transform the organism into a single-celled chemical factory. Using biological processes, we can produce more complex… read more here.
Keywords: engineering; production; metabolic engineering; escherichia coli ... See more keywords
Engineering Escherichia coli-Derived Nanoparticles for Vaccine Development
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DOI: 10.3390/vaccines12111287
Abstract: The development of effective vaccines necessitates a delicate balance between maximizing immunogenicity and minimizing safety concerns. Subunit vaccines, while generally considered safe, often fail to elicit robust and durable immune responses. Nanotechnology presents a promising… read more here.
Keywords: escherichia coli; development; engineering escherichia; coli ... See more keywords