Engineering Fe(II)/α-Ketoglutarate-Dependent Halogenases and Desaturases.
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DOI: 10.1021/acs.biochem.2c00115
Abstract: Fe(II)/α-ketoglutarate-dependent dioxygenases (α-KGDs) are widespread enzymes in aerobic biology and serve a remarkable array of biological functions, including roles in collagen biosynthesis, plant and animal development, transcriptional regulation, nucleic acid modification, and secondary metabolite biosynthesis.… read more here.
Keywords: engineering ketoglutarate; ketoglutarate dependent; biology; engineering ... See more keywords