Quorum sensing-based metabolic engineering of the precursor supply in Streptomyces coelicolor to improve heterologous production of neoaureothin.
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DOI: 10.1002/bit.28400
Abstract: Streptomyces are important industrial bacteria that produce pharmaceutically valuable polyketides. However, mass production on an industrial scale is limited by low productivity, which can be overcome through metabolic engineering and the synthetic biology of the… read more here.
Keywords: metabolic engineering; production; quorum sensing; engineering precursor ... See more keywords