Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Journal"
DOI: 10.1002/biot.201700601
Abstract: Thanks to its ease of use, modularity, and scalability, the clustered regularly interspaced short palindromic repeats (CRISPR) system has been increasingly used in the design and engineering of Saccharomyces cerevisiae, one of the most popular… read more here.
Keywords: engineering; saccharomyces cerevisiae; crispr; system ... See more keywords
Metabolic engineering of Saccharomyces cerevisiae for production of spermidine under optimal culture conditions.
Sign Up to like & getrecommendations! Published in 2017 at "Enzyme and microbial technology"
DOI: 10.1016/j.enzmictec.2017.03.008
Abstract: Spermidine is a polyamine compound exhibiting important biological activities, such as increasing lifespan, inflammation reduction, and plant growth control. As such, many applications of spermidine as a bio-modulating agent are anticipated. However, sustainable and scalable… read more here.
Keywords: saccharomyces cerevisiae; production; production spermidine; metabolic engineering ... See more keywords
Metabolic Engineering of Saccharomyces cerevisiae for Vitamin B5 Production.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c01082
Abstract: Vitamin B5, also called d-pantothenic acid, is an essential vitamin in the human body and is widely used in pharmaceuticals, nutritional supplements, food, and cosmetics. However, few studies have investigated the microbial production of d-pantothenic… read more here.
Keywords: metabolic engineering; pantothenic acid; production; acid ... See more keywords
Metabolic Engineering of Saccharomyces cerevisiae for De Novo Production of Kaempferol.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b01329
Abstract: Kaempferol is a polyphenolic compound with various reported health benefits and thus harbors considerable potential for food-engineering applications. In this study, a high-yield kaempferol-producing cell factory was constructed by multiple strategies, including gene screening, elimination… read more here.
Keywords: production; novo production; metabolic engineering; kaempferol ... See more keywords
Metabolic engineering of Saccharomyces cerevisiae for the synthesis of valuable chemicals.
Sign Up to like & getrecommendations! Published in 2023 at "Critical reviews in biotechnology"
DOI: 10.1080/07388551.2022.2153008
Abstract: In the twenty first century, biotechnology offers great opportunities and solutions to climate change mitigation, energy and food security and resource efficiency. The use of metabolic engineering to modify microorganisms for producing industrially significant chemicals… read more here.
Keywords: synthesis valuable; metabolic engineering; cerevisiae synthesis; engineering saccharomyces ... See more keywords
Engineering Saccharomyces cerevisiae‐based biosensors for copper detection
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.14105
Abstract: Heavy metals, that is Cu(II), are harmful to the environment. There is an increasing demand to develop inexpensive detection methods for heavy metals. Here, we developed a yeast biosensor with reduced‐noise and improved signal output… read more here.
Keywords: copper; detection; engineering saccharomyces; copper ion ... See more keywords
Metabolic Engineering of Saccharomyces cerevisiae for Heterologous Carnosic Acid Production
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.916605
Abstract: Carnosic acid (CA), a phenolic tricyclic diterpene, has many biological effects, including anti-inflammatory, anticancer, antiobesity, and antidiabetic activities. In this study, an efficient biosynthetic pathway was constructed to produce CA in Saccharomyces cerevisiae. First, the… read more here.
Keywords: metabolic engineering; production; engineering saccharomyces; saccharomyces cerevisiae ... See more keywords
Metabolic Engineering of Saccharomyces cerevisiae to Improve Glucan Biosynthesis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.1812.12049
Abstract: β-Glucan is a chief structural polymer in the cell wall of yeast. β-Glucan has attracted intensive attention because of its wide applications in health protection and cosmetic areas. In the present study, the β-glucan biosynthesis… read more here.
Keywords: biosynthesis; saccharomyces cerevisiae; cerevisiae improve; metabolic engineering ... See more keywords