Rational approach to improve ansamitocin P‐3 production by integrating pathway engineering and substrate feeding in Actinosynnema pretiosum
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DOI: 10.1002/bit.26775
Abstract: Ansamitocin P‐3 (AP‐3) produced by Actinosynnema pretiosum is an important antitumor agent for cancer treatment, but its market supply suffers from a low production titer. The role of AP‐3 unusual glycolate unit supply on its… read more here.
Keywords: production; pathway engineering; actinosynnema pretiosum; substrate feeding ... See more keywords