Engineering Synthetic CopT/A-Based Genetic Biosensors for miRNA Imaging and Functional Gene Regulation.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c00873
Abstract: Synthetic genetic biosensors that can operate at the transcriptional and translation levels have been widely applied in the control of cellular behaviors and functions. However, the regulation of genetic circuits is often accompanied by the… read more here.
Keywords: synthetic copt; engineering synthetic; gene; genetic biosensors ... See more keywords
Engineering a Synthetic Dopamine-Responsive Riboswitch for In Vitro Biosensing.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00560
Abstract: The detection of chemicals using natural allosteric transcription factors is a powerful strategy for point-of-use molecular sensing, particularly using fieldable cell-free gene expression (CFE) systems. However, the reliance of detection schemes on characterized protein-based sensors… read more here.
Keywords: dopamine responsive; synthetic dopamine; riboswitch vitro; dopamine ... See more keywords
Toward Methanol-Based Biomanufacturing: Emerging Strategies for Engineering Synthetic Methylotrophy in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00110
Abstract: The global expansion of biomanufacturing is currently limited by the availability of sugar-based microbial feedstocks, which require farmland for cultivation and therefore cannot support large increases in production without impacting the human food supply. One-carbon… read more here.
Keywords: synthetic methylotrophy; methylotrophy; toward methanol; engineering synthetic ... See more keywords
Actinosomes: Condensate-Templated Containers for Engineering Synthetic Cells
Sign Up to like & getrecommendations! Published in 2022 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.2c00290
Abstract: Engineering synthetic cells has a broad appeal, from understanding living cells to designing novel biomaterials for therapeutics, biosensing, and hybrid interfaces. A key prerequisite to creating synthetic cells is a three-dimensional container capable of orchestrating… read more here.
Keywords: templated containers; condensate templated; engineering synthetic; actinosomes condensate ... See more keywords
An Abiotic Mimic of Endogenous Tissue Inhibitors of Metalloproteinases. Engineering Synthetic Polymer Nanoparticles for use as a Broad-Spectrum Metalloproteinase Inhibitor.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b11481
Abstract: We describe a process for engineering a synthetic polymer nanoparticle (NP) that functions as an effective, broad-spectrum metalloproteinase inhibitor. Inhibition is achieved by incorporating three functional elements in the NP; a group that interacts with… read more here.
Keywords: synthetic polymer; metalloproteinase inhibitor; spectrum metalloproteinase; engineering synthetic ... See more keywords
Engineering a Synthetic Pathway for Gentisate in Pseudomonas Chlororaphis P3
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.622226
Abstract: Pseudomonas chlororaphis P3 has been well-engineered as a platform organism for biologicals production due to enhanced shikimate pathway and excellent physiological and genetic characteristics. Gentisate displays high antiradical and antioxidant activities and is an important… read more here.
Keywords: pseudomonas chlororaphis; synthetic pathway; engineering synthetic; pathway gentisate ... See more keywords
Genetic Engineering and Synthetic Genomics in Yeast to Understand Life and Boost Biotechnology
Sign Up to like & getrecommendations! Published in 2020 at "Bioengineering"
DOI: 10.3390/bioengineering7040137
Abstract: The field of genetic engineering was born in 1973 with the “construction of biologically functional bacterial plasmids in vitro”. Since then, a vast number of technologies have been developed allowing large-scale reading and writing of… read more here.
Keywords: biotechnology; engineering synthetic; yeast; genetic engineering ... See more keywords
Metabolic Engineering and Synthetic Biology Approaches for the Heterologous Production of Aromatic Polyketides
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108923
Abstract: Polyketides are a diverse set of natural products with versatile applications as pharmaceuticals, nutraceuticals, and cosmetics, to name a few. Of several types of polyketides, aromatic polyketides comprising type II and III polyketides contain many… read more here.
Keywords: metabolic engineering; aromatic polyketides; engineering synthetic; biology ... See more keywords
Special Issue “Metabolic Engineering and Synthetic Biology Volume 2”
Sign Up to like & getrecommendations! Published in 2021 at "Metabolites"
DOI: 10.3390/metabo11010035
Abstract: In times of ever-increasing demand for chemicals and the subsequent increase in CO2 in the atmosphere, we have to intensify our efforts to establish a circular (bio) economy [...]. read more here.
Keywords: metabolic engineering; synthetic biology; engineering synthetic; issue metabolic ... See more keywords