Metabolic engineering a yeast to produce astaxanthin.
Sign Up to like & getrecommendations! Published in 2017 at "Bioresource technology"
DOI: 10.1016/j.biortech.2017.07.116
Abstract: In this study, an astaxanthin-biosynthesis Kluyveromyces marxianus strain Sm23 was first constructed, which could produce 31µg/g DCW astaxanthin. Then, repeated genome integration of the key astaxanthin biosynthesis genes Hpchyb and bkt was done to increase… read more here.
Keywords: metabolic engineering; engineering yeast; yield; yeast produce ... See more keywords
Pathway engineering in yeast for synthesizing the complex polyketide bikaverin
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DOI: 10.1038/s41467-020-19984-3
Abstract: Fungal polyketides display remarkable structural diversity and bioactivity, and therefore the biosynthesis and engineering of this large class of molecules is therapeutically significant. Here, we successfully recode, construct and characterize the biosynthetic pathway of bikaverin,… read more here.
Keywords: engineering; bikaverin; pathway engineering; engineering yeast ... See more keywords
Engineering yeast metabolism for production of terpenoids for use as perfume ingredients, pharmaceuticals and biofuels.
Sign Up to like & getrecommendations! Published in 2017 at "FEMS yeast research"
DOI: 10.1093/femsyr/fox080
Abstract: Terpenoids represent a large class of natural products with significant commercial applications. These chemicals are currently mainly obtained through extraction from plants and microbes or through chemical synthesis. However, these sources often face challenges of… read more here.
Keywords: yeast metabolism; ingredients pharmaceuticals; engineering yeast; yeast ... See more keywords