Articles with "engraftment" as a keyword



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Improving Hepatocyte Engraftment Following Hepatocyte Transplantation Using Repeated Reversible Portal Vein Embolization in Rats

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Published in 2019 at "Liver Transplantation"

DOI: 10.1002/lt.25364

Abstract: Hepatocyte transplantation (HT) has emerged as a promising alternative to orthotopic liver transplantation, yet liver preconditioning is needed to promote hepatocyte engraftment. A method of temporary occlusion of the portal flow called reversible portal vein… read more here.

Keywords: hepatocyte engraftment; reversible portal; engraftment; portal vein ... See more keywords

Correlation of the Effective Residual Vital (HPC) Dose with Engraftment Kinetics in Autologous Transplantation Amongst Myeloma and Lymphoma Patients

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Published in 2020 at "Biology of Blood and Marrow Transplantation"

DOI: 10.1016/j.bbmt.2019.12.489

Abstract: Introduction In clinical practice, a hematopoietic progenitor cell (HPC) dose of 2 million CD34+ cells/kg is the desired minimum needed for timely neutrophil and platelet (PLT) engraftment in autologous hematopoietic cell transplantation (HCT). Patients frequently… read more here.

Keywords: lymphoma; engraftment; plt engraftment; correlation ... See more keywords
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MECHANISM OF IMPROVED HUMAN HEMATOPOIETIC STEM CELL ENGRAFTMENT IN NON-CONDITIONED NSGW41 MICE

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Published in 2019 at "Experimental Hematology"

DOI: 10.1016/j.exphem.2019.06.425

Abstract: Humanized mouse models enable the study of human hematopoietic stem cell (HSC) function in vivo. However, human HSC engraftment and self-renewal are still hampered in xenotransplantation settings restricting the study of mechanisms regulating human HSC… read more here.

Keywords: engraftment; stem cell; nsgw41 mice; hscs ... See more keywords
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The influence of cell concentration at cryopreservation on neutrophil engraftment after autologous peripheral blood stem cell transplantation

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Published in 2018 at "Hematology, Transfusion and Cell Therapy"

DOI: 10.1016/j.htct.2018.01.007

Abstract: Background Peripheral blood stem cell concentrations are traditionally adjusted to 20–40 × 106 leukocytes/mL prior to freezing. This low cell concentration at cryopreservation implies larger volumes with more dimethyl sulfoxide being used, and higher cost… read more here.

Keywords: engraftment; stem cell; cell concentration; concentration ... See more keywords
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The Spindle Assembly Checkpoint Is Required for Hematopoietic Progenitor Cell Engraftment

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Published in 2017 at "Stem Cell Reports"

DOI: 10.1016/j.stemcr.2017.09.017

Abstract: Summary The spindle assembly checkpoint plays a pivotal role in preventing aneuploidy and transformation. Many studies demonstrate impairment of this checkpoint in cancer cells. While leukemia is frequently driven by transformed hematopoietic stem and progenitor… read more here.

Keywords: spindle assembly; engraftment; checkpoint; progenitor ... See more keywords
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Successful Secondary Engraftment of Pancreatic Ductal Adenocarcinoma and Cholangiocarcinoma Patient-Derived Xenografts After Previous Failed Primary Engraftment1

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Published in 2019 at "Translational Oncology"

DOI: 10.1016/j.tranon.2018.09.008

Abstract: BACKGROUND: Patient-derived xenografts (PDX) provide histologically accurate cancer models that recapitulate patient malignant phenotype and allow for highly correlative oncologic in-vivo downstream translational studies. Primary PDX engraftment failure has significant negative consequences on programmatic efficiency… read more here.

Keywords: engraftment; derived xenografts; pdx; secondary engraftment ... See more keywords
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Long-Term Hematopoietic Engraftment of Congenic Amniotic Fluid Stem Cells After in Utero Intraperitoneal Transplantation to Immune Competent Mice

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Published in 2018 at "Stem Cells and Development"

DOI: 10.1089/scd.2017.0116

Abstract: Clinical success of in utero transplantation (IUT) using allogeneic hematopoietic stem cells (HSCs) has been limited to fetuses that lack an immune response to allogeneic cells due to severe immunological defects, and where transplanted genetically… read more here.

Keywords: engraftment; long term; allogeneic; amniotic fluid ... See more keywords
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Factors affecting polyglycolic acid sheet engraftment success for covering mucosal defects from head and neck surgery.

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Published in 2023 at "Japanese journal of clinical oncology"

DOI: 10.1093/jjco/hyad035

Abstract: BACKGROUND Polyglycolic acid (PGA) sheets have been used with fibrin glue to cover extensive mucosal defects in oral and pharyngeal surgery; however, the sheets can fall off before wound healing is completed. Hence, prolonged fasting… read more here.

Keywords: engraftment; polyglycolic acid; fasting duration; mucosal defects ... See more keywords
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The Viability of Hematopoietic Progenitor Cell Grafts after Cryopreservation Does Not Predict Delayed Engraftment in Allogeneic Hematopoietic Stem Cell Transplantation.

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Published in 2022 at "Laboratory medicine"

DOI: 10.1093/labmed/lmac042

Abstract: OBJECTIVE Due to the COVID-19 pandemic, more peripheral blood stem cell (PBSC) allogeneic grafts are being frozen and infused thawed. Our objective was to study the influence of graft viability on engraftment outcome in patients… read more here.

Keywords: cell; time; stem cell; engraftment ... See more keywords
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Herombopag promotes platelet engraftment and decreases platelet transfusion after allogeneic hematopoietic stem cell transplantation

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Published in 2023 at "European Journal of Haematology"

DOI: 10.1111/ejh.13925

Abstract: The delayed platelet engraftment associated with allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is a common complication and often results in increased transplant‐related complications. A single‐center, prospective, investigator‐initiated pilot study was conducted to explore whether herombopag,… read more here.

Keywords: allogeneic hematopoietic; engraftment; platelet engraftment; range ... See more keywords
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Synthetic matrix enhances transplanted satellite cell engraftment in dystrophic and aged skeletal muscle with comorbid trauma

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Published in 2018 at "Science Advances"

DOI: 10.1126/sciadv.aar4008

Abstract: Synthetic designer matrix enhances muscle stem cell function and engraftment in injured dystrophic and aged skeletal muscles. Muscle satellite cells (MuSCs) play a central role in muscle regeneration, but their quantity and function decline with… read more here.

Keywords: engraftment; muscle; matrix enhances; dystrophic aged ... See more keywords