Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons
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DOI: 10.7554/elife.50260
Abstract: Mitophagy, the selective removal of damaged mitochondria, is thought to be critical to maintain neuronal homeostasis. Mutations of proteins in the pathway cause neurodegenerative diseases, suggesting defective mitochondrial turnover contributes to neurodegeneration. In primary rat… read more here.
Keywords: optineurin mediated; mitochondria rate; engulfed mitochondria; rate limiting ... See more keywords