Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202506827
Abstract: Efficient modulation of pivotal immune‐regulatory molecules to leverage the tumor microenvironment (TME) and enhance therapeutic effects remains an ideal yet challenging goal. TGFβ1 represents a critical therapeutic target as a key cytokine involved in immune… read more here.
Keywords: tgf sequestration; dna origami; tumor; enhance ... See more keywords
Repurposing of quinoline alkaloids identifies their ability to enhance doxorubicin‐induced sub‐G0/G1 phase cell cycle arrest and apoptosis in cervical and hepatocellular carcinoma cells
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1999
Abstract: The ability of quinoline alkaloids (cinchonine, cinchonidine, quinine, and quinidine) to sensitize different human cancer cell lines to doxorubicin (DOX)‐induced cell death was evaluated. Cell viability was analyzed using 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide (MTT) assay and the… read more here.
Keywords: dox induced; quinoline alkaloids; apoptosis; ability ... See more keywords
Incorporating a Polyethyleneglycol Linker to Enhance the Hydrophilicity of Mitochondria‐Targeted Triphenylphosphonium Constructs
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202200774
Abstract: The targeting of bioactive molecules and probes to mitochondria can be achieved by coupling to the lipophilic triphenyl phosphonium (TPP) cation, which accumulates several hundred‐fold within mitochondria in response to the mitochondrial membrane potential (Δψm).… read more here.
Keywords: mitochondria targeted; linker; enhance; within mitochondria ... See more keywords
Molecular Modeling is an Enabling Approach to Complement and Enhance Channelopathy Research.
Sign Up to like & getrecommendations! Published in 2022 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c190047
Abstract: Hundreds of human membrane proteins form channels that transport necessary ions and compounds, including drugs and metabolites, yet details of their normal function or how function is altered by genetic variants to cause diseases are… read more here.
Keywords: enabling approach; function; modeling enabling; molecular modeling ... See more keywords
Data imputation in deep neural network to enhance breast cancer detection
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Imaging Systems and Technology"
DOI: 10.1002/ima.22743
Abstract: Breast cancer is one of the most precarious cancers that claims many women's' lives every year. The existing automated systems for mammography datasets are designed to detect the abnormalities and classify them as benign or… read more here.
Keywords: data imputation; breast cancer; enhance; cancer ... See more keywords
Water Management to Enhance Ecosystem Services in a Coastal Wetland in Taiwan
Sign Up to like & getrecommendations! Published in 2018 at "Irrigation and Drainage"
DOI: 10.1002/ird.2234
Abstract: Wetlands provide multiple ecosystem services, and wetland hydrology is one of the key determinants of wetland function. Budai Salt Pan Wetland provides at least 11 ecosystem services, i.e. food provision, genetic materials, climate regulation, water… read more here.
Keywords: ecosystem; enhance; water management; ecosystem services ... See more keywords
Using natural language processing of clinical text to enhance identification of opioid‐related overdoses in electronic health records data
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4810
Abstract: To enhance automated methods for accurately identifying opioid‐related overdoses and classifying types of overdose using electronic health record (EHR) databases. read more here.
Keywords: related overdoses; opioid related; electronic health; enhance ... See more keywords
How opportunistic mobile monitoring can enhance air quality assessment?
Sign Up to like & getrecommendations! Published in 2024 at "GeoInformatica"
DOI: 10.1007/s10707-024-00516-w
Abstract: The deteriorating air quality in urban areas, particularly in developing countries, has led to increased attention being paid to the issue. Daily reports of air pollution are essential to effectively manage public health risks. Pollution… read more here.
Keywords: opportunistic mobile; air; mobile monitoring; air quality ... See more keywords
Commentary on: How Schools Enhance the Development of Young People’s Resilience, by Ungar, Connelly, Liebenberg, and Theron, 2017
Sign Up to like & getrecommendations! Published in 2019 at "Social Indicators Research"
DOI: 10.1007/s11205-018-1971-7
Abstract: Abstract This commentary aims to expand on the well-articulated review on youth resilience by Ungar et al. (2017), with reference to promoting resilience among young people residing in Western settings. In this commentary, we highlight… read more here.
Keywords: resilience ungar; resilience; commentary; enhance ... See more keywords
Nicotiana tabacum-associated bioengineered Pseudomonas putida can enhance rhizoremediation of soil containing 2,4-dinitrotoluene
Sign Up to like & getrecommendations! Published in 2020 at "3 Biotech"
DOI: 10.1007/s13205-020-02395-y
Abstract: Rhizoremediation processes are based on plant-bacteria interactions and can be effectively used for cleaning many pollutants from the environment to overcome the constraints of individual phytoremediation. Here, 1 mM and 1.5 mM concentrations of 2,4-dinitrotoluene… read more here.
Keywords: rhizoremediation; tabacum; pseudomonas putida; nicotiana tabacum ... See more keywords
Defect engineering in SnO2 nanomaterials: Pathway to enhance the biohydrogen production from agricultural residue of corn stover
Sign Up to like & getrecommendations! Published in 2020 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2020.100850
Abstract: Abstract It has been shown that altering nanomaterials through surface defects engineering (creation of oxygen vacancies) can be possible route to enhance the hydrogen production from agricultural residue of corn stover. Surface defects of oxygen… read more here.
Keywords: agricultural residue; production; hydrogen production; production agricultural ... See more keywords