Microbiota Manipulated to Enhance Anticancer Immunity.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-nd2019-004
Abstract: Oncologists are testing fecal transplants and other microbiome-based products in combination with checkpoint inhibitors in an effort to increase and enhance responses. However, questions remain about how the microbes affect host immunity and which preparations… read more here.
Keywords: immunity; manipulated enhance; anticancer immunity; enhance anticancer ... See more keywords
Targeting PARP1 to Enhance Anticancer Checkpoint Immunotherapy Response: Rationale and Clinical Implications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.816642
Abstract: Reinvigorating the antitumor immune response using immune checkpoint inhibitors (ICIs) has revolutionized the treatment of several malignancies. However, extended use of ICIs has resulted in a cancer-specific response. In tumors considered to be less immunogenic,… read more here.
Keywords: enhance anticancer; checkpoint; parp1 enhance; anticancer checkpoint ... See more keywords