Ultrasound-Triggered Piezocatalysis for Selectively Controlled NO Gas and Chemodrug Release to Enhance Drug Penetration in Pancreatic Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.2c09948
Abstract: Nitric oxide (NO) is drawing widespread attention in treating pancreatic ductal adenocarcinoma (PDAC) as a safe and therapeutically efficient technique through modulating the dense fibrotic stroma in the tumor microenvironment to enhance drug penetration. Considerable… read more here.
Keywords: tumor; enhance drug; release; cpt ... See more keywords
Does Hyaluronidase Enhance Drug Penetration to Mechanoreceptors?
Sign Up to like & getrecommendations! Published in 2020 at "Skin Pharmacology and Physiology"
DOI: 10.1159/000510890
Abstract: Background: The pharmacological study of mechanoreceptors embedded within tissue is hampered by tissue barriers to applied research drugs. Methods: Hyaluronidase increases the permeability of tissues and is used clinically to facilitate the distribution of injected… read more here.
Keywords: drug penetration; hyaluronidase; penetration mechanoreceptors; hyaluronidase enhance ... See more keywords
MiR-140 targets Wnt1 to inhibit the proliferation and enhance drug sensitivity in osteosarcoma cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2022.68.1.18
Abstract: MicroRNAs (miRNAs) have been documented to function differently in numerous human cancers. Our study planned to investigate the role of microRNA-140 (miR-140) and to identify its possible target in osteosarcoma (OS) to predict their mechanism… read more here.
Keywords: drug sensitivity; enhance drug; mir 140; proliferation ... See more keywords