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Enhanced Cas12a editing in mammalian cells and zebrafish

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0 Published in 2019 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkz184

Abstract: Abstract Type V CRISPR–Cas12a systems provide an alternate nuclease platform to Cas9, with potential advantages for specific genome editing applications. Here we describe improvements to the Cas12a system that facilitate efficient targeted mutagenesis in mammalian… read more here.

Keywords: editing mammalian; cas12a editing; enhanced cas12a; cells zebrafish ... See more keywords