Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9.
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DOI: 10.1016/j.clim.2017.05.016
Abstract: We examined complement-dependent cytotoxicity (CDC) by hexamer formation-enhanced CD20 mAb Hx-7D8 of patient-derived chronic lymphocytic leukemia (CLL) cells that are relatively resistant to CDC. CDC was analyzed in normal human serum (NHS) and serum from… read more here.
Keywords: complement dependent; dependent cytotoxicity; enhanced cd20; cdc ... See more keywords