Articles with "enhanced efficacy" as a keyword



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Multifunctional Mesoporous Hollow Cobalt Sulfide Nanoreactors for Synergistic Chemodynamic/Photodynamic/Photothermal Therapy with Enhanced Efficacy.

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Published in 2022 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.2c15406

Abstract: The unique tumor microenvironment (TME) characteristic of severe hypoxia, overexpressed intracellular glutathione (GSH), and elevated hydrogen peroxide (H2O2) concentration limit the anticancer effect by monotherapy. In this report, glucose oxidase (GOx)-encapsulated mesoporous hollow Co9S8 nanoreactors… read more here.

Keywords: photothermal therapy; therapy; mesoporous hollow; gox pcos ... See more keywords
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Enhanced efficacy of defect passivation and charge extraction for efficient perovskite photovoltaics with a small open circuit voltage loss

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Published in 2019 at "Journal of Materials Chemistry A"

DOI: 10.1039/c9ta01760g

Abstract: A multifunctional 2D polymeric semiconductor was incorporated to provide surprisingly robust efficacy in grain boundary functionalization and defect passivation of perovskite, which suppresses charge recombination and thus affording an illustrious photovoltage of 1.16 V and power… read more here.

Keywords: efficacy; enhanced efficacy; efficacy defect; passivation charge ... See more keywords

A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models

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Published in 2019 at "Clinical Cancer Research"

DOI: 10.1158/1078-0432.ccr-19-2428

Abstract: Purpose: Recent clinical data demonstrate that tumors harboring MET genetic alterations (exon 14 skip mutations and/or gene amplification) respond to small-molecule tyrosine kinase inhibitors, validating MET as a therapeutic target. Although antibody-mediated blockade of the… read more here.

Keywords: enhanced efficacy; tumor models; biparatopic antibody; parental antibodies ... See more keywords

Enhanced Efficacy of PEGylated Liposomal Cisplatin: In Vitro and In Vivo Evaluation

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21020559

Abstract: This study aims to evaluate the potency of cisplatin (Cispt)-loaded liposome (LCispt) and PEGylated liposome (PLCispt) as therapeutic nanoformulations in the treatment of bladder cancer (BC). Cispt was loaded into liposomes using reverse-phase evaporation method,… read more here.

Keywords: plcispt; pegylated liposomal; enhanced efficacy; cisplatin ... See more keywords