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Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c15406
Abstract: The unique tumor microenvironment (TME) characteristic of severe hypoxia, overexpressed intracellular glutathione (GSH), and elevated hydrogen peroxide (H2O2) concentration limit the anticancer effect by monotherapy. In this report, glucose oxidase (GOx)-encapsulated mesoporous hollow Co9S8 nanoreactors…
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Keywords:
photothermal therapy;
therapy;
mesoporous hollow;
gox pcos ... See more keywords
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Published in 2019 at "Journal of Materials Chemistry A"
DOI: 10.1039/c9ta01760g
Abstract: A multifunctional 2D polymeric semiconductor was incorporated to provide surprisingly robust efficacy in grain boundary functionalization and defect passivation of perovskite, which suppresses charge recombination and thus affording an illustrious photovoltage of 1.16 V and power…
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Keywords:
efficacy;
enhanced efficacy;
efficacy defect;
passivation charge ... See more keywords
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Published in 2019 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-19-2428
Abstract: Purpose: Recent clinical data demonstrate that tumors harboring MET genetic alterations (exon 14 skip mutations and/or gene amplification) respond to small-molecule tyrosine kinase inhibitors, validating MET as a therapeutic target. Although antibody-mediated blockade of the…
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Keywords:
enhanced efficacy;
tumor models;
biparatopic antibody;
parental antibodies ... See more keywords
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Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21020559
Abstract: This study aims to evaluate the potency of cisplatin (Cispt)-loaded liposome (LCispt) and PEGylated liposome (PLCispt) as therapeutic nanoformulations in the treatment of bladder cancer (BC). Cispt was loaded into liposomes using reverse-phase evaporation method,…
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Keywords:
plcispt;
pegylated liposomal;
enhanced efficacy;
cisplatin ... See more keywords