Dorsal hippocampal interleukin-1 signaling mediates heroin withdrawal-enhanced fear learning.
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05645-2
Abstract: Converging evidence suggests opioid abuse can increase the incidence and severity of post-traumatic stress disorder (PTSD) in clinical populations. Interestingly, opioid withdrawal alone can produce symptoms similar to those of PTSD. Despite this association, the… read more here.
Keywords: withdrawal; fear learning; heroin withdrawal; enhanced fear ... See more keywords
Hippocampal interleukin-1 mediates stress-enhanced fear learning: A potential role for astrocyte-derived interleukin-1β
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.09.016
Abstract: Post-traumatic stress disorder (PTSD) is associated with immune dysregulation. We have previously shown that severe stress exposure in a preclinical animal model of the disorder, stress-enhanced fear learning (SEFL), is associated with an increase in… read more here.
Keywords: fear learning; sefl; enhanced fear; stress ... See more keywords
Dissociation in Effective Treatment and Behavioral Phenotype Between Stress-Enhanced Fear Learning and Learned Helplessness
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2019.00104
Abstract: Post-traumatic stress disorder (PTSD) is a debilitating disease with relatively high lifetime prevalence. It is marked by a high diversity of symptoms and comorbidity with other psychiatric disease. Furthermore, PTSD has a high level of… read more here.
Keywords: learned helplessness; fear learning; enhanced fear; stress enhanced ... See more keywords