Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant.
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DOI: 10.1016/j.bpj.2021.11.004
Abstract: Connexin-50 (Cx50) is among the most frequently mutated genes associated with congenital cataracts. While most of these disease-linked variants cause loss-of-function due to misfolding or aberrant trafficking, others directly alter channel properties. The mechanistic bases… read more here.
Keywords: enhanced hemichannel; hemichannel; mutant; molecular mechanisms ... See more keywords