Recombinant BCG::Rv2645 elicits enhanced protective immunity compared to BCG in vivo with induced ISGylation-related genes and Th1 and Th17 responses.
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DOI: 10.1016/j.vaccine.2018.04.025
Abstract: There is a need to develop protective vaccines against tuberculosis (TB). Recently, we identified an immunodominant T-cell antigen, Rv2645, from the region of deletion 13 (RD13) of M. tuberculosis (M. tb) H37Rv, which is absent… read more here.
Keywords: enhanced protective; rv2645; th1 th17; related genes ... See more keywords