Enhanced specificity of bimetallic ions via mesoporous confinement for phosphopeptides in human saliva.
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DOI: 10.1016/j.talanta.2021.122587
Abstract: Phosphopeptides were of great significance in disease diagnosis and monitoring its dynamic changes. In this article, we proposed a more efficient method to synthesize a kind of bimetallic mesoporous silica nanomaterials (Fe3O4@mSiO2-PO3-Ti4+/Zr4+) and applied it… read more here.
Keywords: saliva; phosphopeptides human; human saliva; specificity bimetallic ... See more keywords
Enhanced specificity mutations perturb allosteric signaling in CRISPR-Cas9
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DOI: 10.7554/elife.73601
Abstract: CRISPR-Cas9 (clustered regularly interspaced short palindromic repeat and associated Cas9 protein) is a molecular tool with transformative genome editing capabilities. At the molecular level, an intricate allosteric signaling is critical for DNA cleavage, but its… read more here.
Keywords: enhanced specificity; specificity; cas9; crispr cas9 ... See more keywords