Evasion of P-gp mediated efflux and enhancement of bioavailability of protease inhibitor lopinavir by lipidic nanocarriers decorated with TPGS
Sign Up to like & getrecommendations! Published in 2025 at "Particulate Science and Technology"
DOI: 10.1080/02726351.2025.2477270
Abstract: Abstract Lopinavir (LPV) presents significant challenges in HIV management due to its poor permeability and low solubility. This study focuses on the formulation, optimization, and characterization of nanostructured lipid carriers (NLC) enriched with TPGS to… read more here.
Keywords: formulation; lpv; enhancement bioavailability; lopinavir ... See more keywords
Insight Into the various approaches for the enhancement of bioavailability and pharmacological potency of terpenoids: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201024666221130163116
Abstract: Terpenoids are naturally occurring secondary metabolites that consist of isoprene units (i.e., 2-methyl-1,3-butadiene). Terpenoids became recognized because of their diverse pharmacological benefits, such as anti-cancer, anti-inflammatory, antioxidant, analgesic, antibacterial, antifungal, hepatoprotective, antiviral, and antiparasitic activities.… read more here.
Keywords: enhancement bioavailability; bioavailability; approaches enhancement; insight various ... See more keywords