Abstract IA03: Subgroup-specific enhancer hijacking in medulloblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.pedca17-ia03
Abstract: In recent years, next-generation sequencing has uncovered the spectrum of driver genes and molecular processes contributing to most cancer entities, including pediatric cancer. This holds true for medulloblastoma (MB), the most common malignant childhood brain… read more here.
Keywords: subgroup specific; medulloblastoma; enhancer hijacking; cancer ... See more keywords
Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription.
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DOI: 10.1182/blood-2022-169565
Abstract: Structural variants (SVs) involving enhancer hijacking can rewire chromatin topologies to cause oncogene activation in human cancers including hematologic malignancies; however, due to the lack of tools to assess their effects on gene regulation and… read more here.
Keywords: transcription; enhancer hijacking; chromatin; structural variation ... See more keywords