Oncogenic transcription factors instruct promoter-enhancer hubs in individual triple negative breast cancer cells
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DOI: 10.1126/sciadv.adl4043
Abstract: Sequencing-based mapping of ensemble pairwise interactions among regulatory elements support the existence of topological assemblies known as promoter-enhancer hubs or cliques in cancer. Yet, prevalence, regulators, and functions of promoter-enhancer hubs in individual cancer cells… read more here.
Keywords: enhancer hubs; cancer; enhancer; promoter enhancer ... See more keywords