Computational enhancer prediction: evaluation and improvements
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-2781-x
Abstract: BackgroundIdentifying transcriptional enhancers and other cis-regulatory modules (CRMs) is an important goal of post-sequencing genome annotation. Computational approaches provide a useful complement to empirical methods for CRM discovery, but it is critical that we develop… read more here.
Keywords: pcrmeval; sensitivity; evaluation; enhancer prediction ... See more keywords
Enhancer prediction in the human genome by probabilistic modelling of the chromatin feature patterns
Sign Up to like & getrecommendations! Published in 2020 at "BMC Bioinformatics"
DOI: 10.1186/s12859-020-03621-3
Abstract: Background The binding sites of transcription factors (TFs) and the localisation of histone modifications in the human genome can be quantified by the chromatin immunoprecipitation assay coupled with next-generation sequencing (ChIP-seq). The resulting chromatin feature… read more here.
Keywords: human genome; preprint; chromatin feature; enhancer prediction ... See more keywords