Sign Up to like & get
recommendations!
0
Published in 2018 at "Cancer cell"
DOI: 10.1016/j.ccell.2018.11.005
Abstract: Drug resistance represents a major challenge to achieving durable responses to cancer therapeutics. Resistance mechanisms to epigenetically targeted drugs remain largely unexplored. We used bromodomain and extra-terminal domain (BET) inhibition in neuroblastoma as a prototype…
read more here.
Keywords:
targeted therapy;
epigenetic targeted;
resistance epigenetic;
resistance ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084258
Abstract: The glucocorticoid receptor (GR, also known as NR3C1) coordinates molecular responses to stress. It is a potent transcription activator and repressor that influences hundreds of genes. Enhancers are non-coding DNA regions outside of the core…
read more here.
Keywords:
gene expression;
non coding;
expression;
enhancer remodeling ... See more keywords