Integrative genomic analysis predicts novel functional enhancer-SNPs for bone mineral density
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DOI: 10.1007/s00439-019-01971-4
Abstract: Osteoporosis is a skeletal disorder characterized by low bone mineral density (BMD) and deterioration of bone microarchitecture. To identify novel genetic loci underlying osteoporosis, an effective strategy is to focus on scanning of variants with… read more here.
Keywords: bone mineral; snps; enhancer snps; mineral density ... See more keywords
Integrative functional analysis of super enhancer SNPs for coronary artery disease
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DOI: 10.1038/s10038-018-0422-2
Abstract: Clinical research in coronary artery disease (CAD) primarily focused on genetic variants located in protein-coding regions. Recently, mutations fall within non-coding regions have been suggested to be essential to the pathogenesis of human complex disease.… read more here.
Keywords: cad; disease; super enhancer; enhancer snps ... See more keywords