Hypoxia enhances H2O2-mediated upregulation of hepcidin: Evidence for NOX4-mediated iron regulation
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DOI: 10.1016/j.redox.2018.02.005
Abstract: The exact regulation of the liver-secreted peptide hepcidin, the key regulator of systemic iron homeostasis, is still poorly understood. It is potently induced by iron, inflammation, cytokines or H2O2 but conflicting results have been reported… read more here.
Keywords: h2o2 mediated; hepcidin; hypoxia; iron ... See more keywords