Enhancing the Anti-tumor Potency of a Novel Siglec-15 Antibody by Engineering its Fc-mediated Effector Functions
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DOI: 10.1097/cji.0000000000000465
Abstract: Siglec-15, an inhibitory immune checkpoint, is an emerging target in cancer immunotherapy. Blocking the function of Siglec-15 is an excellent strategy for cancer treatment and antibody blockade has been used to target Siglec-15. However, whether… read more here.
Keywords: enhancing anti; potency; mediated effector; effector functions ... See more keywords