Enhancing Repair of Oxidative DNA Damage with Small-Molecule Activators of MTH1.
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DOI: 10.1021/acschembio.2c00038
Abstract: Impaired DNA repair activity has been shown to greatly increase rates of cancer clinically. It has been hypothesized that upregulating repair activity in susceptible individuals may be a useful strategy for inhibiting tumorigenesis. Here, we… read more here.
Keywords: enhancing repair; dna; oxidative dna; dna damage ... See more keywords