On the occurrence and enigmatic functions of mixed (chemical plus electrical) synapses in the mammalian CNS
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.09.021
Abstract: Electrical synapses with diverse configurations and functions occur at a variety of interneuronal appositions, thereby significantly expanding the physiological complexity of neuronal circuitry over that provided solely by chemical synapses. Gap junctions between apposed dendritic… read more here.
Keywords: enigmatic functions; occurrence enigmatic; synapses mammalian; mammalian cns ... See more keywords
Enigmatic functions of ATP8B1: cholestasis, inflammation, phosphoinositide flipping, and cellular homeostasis.
Sign Up to like & getrecommendations! Published in 2025 at "Cell cycle"
DOI: 10.1080/15384101.2025.2574275
Abstract: ABSTRACT Mutations in ATP8B1 cause a spectrum of cholestatic liver disease, ranging from Progressive-Familial-Intrahepatic-Cholestasis type-1 (PFIC1) to Benign-Recurrent-Intrahepatic-Cholestasis type-1 (BRIC1). Manifestations of PFIC1 include severe pruritus, jaundice, and liver damage. Extrahepatic features sometimes observed in… read more here.
Keywords: cholestasis inflammation; cholestasis; functions atp8b1; atp8b1 cholestasis ... See more keywords
Unknown/enigmatic functions of extracellular ASC
Sign Up to like & getrecommendations! Published in 2021 at "Immunology"
DOI: 10.1111/imm.13375
Abstract: Apoptosis‐associated speck‐like protein containing a caspase recruit domain (ASC), encoded by PYCARD gene, is a 22 kDa small molecule, which aggregates into ASC specks during inflammasome activation. ASC protein is an adaptor protein present in… read more here.
Keywords: enigmatic functions; asc; extracellular asc; asc specks ... See more keywords