Transcription control by the ENL YEATS domain in acute leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature21688
Abstract: Recurrent chromosomal translocations producing a chimaeric MLL oncogene give rise to a highly aggressive acute leukaemia associated with poor clinical outcome. The preferential involvement of chromatin-associated factors as MLL fusion partners belies a dependency on… read more here.
Keywords: transcription control; enl; yeats domain; acute leukaemia ... See more keywords
Regulatory T cells in erythema nodosum leprosum maintain anti-inflammatory function
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010641
Abstract: Background The numbers of circulating regulatory T cells (Tregs) are increased in lepromatous leprosy (LL) but reduced in erythema nodosum leprosum (ENL), the inflammatory complication of LL. It is unclear whether the suppressive function of… read more here.
Keywords: function; cd25 cells; cd25; depletion cd25 ... See more keywords
Neutrophil NETworking in ENL: Potential as a Putative Biomarker: Future Insights
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.697804
Abstract: Erythema nodosum leprosum (ENL), also known as type 2 reaction (T2R) is an immune complex mediated (type III hypersensitivity) reactional state encountered in patients with borderline lepromatous and lepromatous leprosy (BL and LL) either before,… read more here.
Keywords: networking enl; biomarker; treatment; enl ... See more keywords
Effect of a Flaxseed Lignan Intervention on Circulating Bile Acids in a Placebo-Controlled Randomized, Crossover Trial
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12061837
Abstract: Plant lignans and their microbial metabolites, e.g., enterolactone (ENL), may affect bile acid (BA) metabolism through interaction with hepatic receptors. We evaluated the effects of a flaxseed lignan extract (50 mg/day secoisolariciresinol diglucoside) compared to… read more here.
Keywords: intervention; metabolism; randomized crossover; enl ... See more keywords