Assessment of Risk Factors and Clinical Importance of Enlarged Perivascular Spaces by Whole-Brain Investigation in the Multi-Ethnic Study of Atherosclerosis
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.9196
Abstract: Key Points Question What is the clinical importance of enlarged perivascular spaces detected on brain magnetic resonance imaging? Findings This cross-sectional study was conducted in a multiethnic sample of 1026 individuals living in the community.… read more here.
Keywords: enlarged perivascular; perivascular spaces; brain; clinical importance ... See more keywords
Association of Apolipoprotein E ɛ4 allele with Enlarged Perivascular Spaces.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of neurology"
DOI: 10.1002/ana.26364
Abstract: OBJECTIVE Enlarged perivascular spaces have emerged as markers of cerebral small vessel disease and are linked to perivascular drainage dysfunction. The Apolipoprotein E ɛ4 allele is the strongest genetic risk factor for cerebral amyloid angiopathy… read more here.
Keywords: enlarged perivascular; apolipoprotein allele; perivascular spaces; burden enlarged ... See more keywords
Role of Enlarged Perivascular Space in the Temporal Lobe in Cerebral Amyloidosis
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26601
Abstract: Although growing evidence suggests that perivascular space (PVS) serves as a clearance route for amyloid and tau, the association between enlarged PVS (EPVS) and Alzheimer disease is highly inconsistent across studies. As the conventional visual… read more here.
Keywords: temporal lobe; enlarged perivascular; role enlarged; perivascular space ... See more keywords
Aggravation of Enlarged Perivascular Spaces in the Centrum Semiovale of Patients with Aneurysmal Subarachnoid Hemorrhage
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Neuroradiology"
DOI: 10.1007/s00062-021-01098-y
Abstract: This study aimed to investigate whether enlarged perivascular spaces (ePVS) within the basal ganglia (BG) or centrum semiovale (CSO) aggravate in patients with aneurysmal subarachnoid hemorrhage (aSAH). We retrospectively evaluated 139 patients who had undergone… read more here.
Keywords: perivascular spaces; enlarged perivascular; aggravation; aggravation epvs ... See more keywords
Elevated hemoglobin is independently associated with enlarged perivascular spaces in the central semiovale
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82327-9
Abstract: Enlarged perivascular spaces (EPVS) are widely considered as a feature of cerebral small vessel diseases (SVD), but its underlying pathology is still under active investigation. The aim of this study was to explore the association… read more here.
Keywords: perivascular spaces; enlarged perivascular; high degree; hemoglobin ... See more keywords
In patients who had a stroke or TIA, enlarged perivascular spaces in basal ganglia may cause future haemorrhagic strokes
Sign Up to like & getrecommendations! Published in 2023 at "Stroke and Vascular Neurology"
DOI: 10.1136/svn-2022-002157
Abstract: Introduction It remains unclear whether enlarged perivascular spaces (EPVS) predict poor clinical outcomes in patients with acute ischaemic stroke (AIS) or transient ischaemic attack (TIA). Method Data were obtained from the Third China National Stroke… read more here.
Keywords: epvs; year; enlarged perivascular; perivascular spaces ... See more keywords
MR Imaging-based Multimodal Autoidentification of Perivascular Spaces (mMAPS): Automated Morphologic Segmentation of Enlarged Perivascular Spaces at Clinical Field Strength.
Sign Up to like & getrecommendations! Published in 2018 at "Radiology"
DOI: 10.1148/radiol.2017170205
Abstract: Purpose To describe a fully automated segmentation method that yields object-based morphologic estimates of enlarged perivascular spaces (ePVSs) in clinical-field-strength (3.0-T) magnetic resonance (MR) imaging data. Materials and Methods In this HIPAA-compliant study, MR imaging… read more here.
Keywords: perivascular spaces; enlarged perivascular; field strength; multimodal autoidentification ... See more keywords
Chronic Kidney Disease as Risk Factor for Enlarged Perivascular Spaces in Patients With Stroke and Relation to Racial Group
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DOI: 10.1161/strokeaha.119.028688
Abstract: Supplemental Digital Content is available in the text. Background and Purpose: Enlarged perivascular spaces (EPVS) are considered subclinical markers of small vessel disease, associated with increased risk of stroke and dementia. Increasing evidence links chronic… read more here.
Keywords: enlarged perivascular; patients stroke; perivascular spaces; racial group ... See more keywords
The relationship between blood–brain barrier permeability and enlarged perivascular spaces: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s204269
Abstract: Purpose: Enlarged perivascular spaces (EPVS) have been widely considered as a feature of cerebral small vessel disease (cSVD) but the pathogenesis of EPVS remains unclear. Compromised blood–brain barrier (BBB) integrity may play a role since… read more here.
Keywords: enlarged perivascular; blood; epvs; study ... See more keywords
Presence of enlarged perivascular spaces is associated with reduced processing speed in asymptomatic, working-aged adults.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2102051
Abstract: BACKGROUND Enlarged perivascular spaces (ePVS) and white matter hyperintensities (WMHs) are recognised neuroimaging lesions for symptomatic and/or occult cerebral small vessel disease (CSVD) that are linked with the predisposition to cardiocerebrovascular risk and neurocognitive impairment.… read more here.
Keywords: working aged; asymptomatic working; aged adults; perivascular spaces ... See more keywords
Lesion Volume in Relapsing Multiple Sclerosis is Associated with Perivascular Space Enlargement at the Level of the Basal Ganglia
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a7398
Abstract: BACKGROUND AND PURPOSE: Perivascular spaces surround the blood vessels of the brain and are involved in neuroimmune functions and clearance of metabolites via the glymphatic system of the brain. Enlarged perivascular spaces could be a… read more here.
Keywords: level basal; perivascular spaces; enlarged perivascular; brain ... See more keywords