Targeting Endothelial ENO1 (Alpha-Enolase) -PI3K-Akt-mTOR Axis Alleviates Hypoxic Pulmonary Hypertension.
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DOI: 10.1161/hypertensionaha.122.19857
Abstract: BACKGROUND It has been shown that glycolytic protein ENO1 (alpha-enolase) contributes to the pathogenesis of pulmonary hypertension through acting smooth muscle cells; however, the roles of ENO1-caused endothelial and mitochondrial dysfunctions in Group 3 pulmonary… read more here.
Keywords: pi3k akt; pulmonary hypertension; hypertension; hypoxic pulmonary ... See more keywords