Effect of Rivaroxaban vs Enoxaparin on Major Cardiac Adverse Events and Bleeding Risk in the Acute Phase of Acute Coronary Syndrome
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.55709
Abstract: Key Points Question Is short-term oral rivaroxaban a noninferior alternative to parenteral enoxaparin in the acute phase of acute coronary syndrome (ACS)? Findings This equivalence and noninferiority trial including 2046 patients found that short-term rivaroxaban… read more here.
Keywords: coronary syndrome; acute phase; acute coronary; phase acute ... See more keywords
Association of Changes in Antithrombin Activity Over Time With Responsiveness to Enoxaparin Prophylaxis and Risk of Trauma-Related Venous Thromboembolism.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA surgery"
DOI: 10.1001/jamasurg.2022.2214
Abstract: Importance Venous thromboembolism (VTE) affects 2% to 20% of recovering trauma patients, despite aggressive prophylaxis with enoxaparin. Antithrombin is a primary circulating anticoagulant and crucial component of enoxaparin thromboprophylaxis. Approximately 20% of trauma patients present… read more here.
Keywords: enoxaparin; median iqr; antithrombin activity; trauma ... See more keywords
Use of Real‐World Data and Physiologically‐Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2618
Abstract: Dosing guidance for children with obesity is often unknown despite the fact that nearly 20% of US children are classified as obese. Enoxaparin, a commonly prescribed low‐molecular‐weight heparin, is dosed based on body weight irrespective… read more here.
Keywords: children without; without obesity; children obesity; physiologically based ... See more keywords
Impact of antithrombin III and enoxaparin dosage adjustment on prophylactic anti-Xa concentrations in trauma patients at high risk for venous thromboembolism: a randomized pilot trial
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-021-02478-4
Abstract: The impact of antithrombin III activity (AT-III) on prophylactic enoxaparin anti-factor Xa concentration (anti-Xa) is unknown in high-risk trauma patients. So too is the optimal anti-Xa-adjusted enoxaparin dosage. This prospective, randomized, pilot study sought to… read more here.
Keywords: iii; goal; adjustment; enoxaparin ... See more keywords
A Caprini Risk Score-Based Cost-Effectiveness Analysis of Enoxaparin for the Thromboprophylaxis of Patients After Nonorthopedic Surgery in a Chinese Healthcare Setting
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Drug Investigation"
DOI: 10.1007/s40261-019-00876-4
Abstract: Background Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), is an important cause of post-surgery morbidity and mortality. However, it is unclear whether thromboprophylaxis with the low-molecular-weight heparin (LMWH) enoxaparin… read more here.
Keywords: surgery; cost; enoxaparin; caprini risk ... See more keywords
INCIDENTAL AND ASYMPTOMATIC SPLENIC INFRACTION AND INFRARENAL THORMBUS IN A PATIENT WITH COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2021.07.318
Abstract: TOPIC: Chest Infections TYPE: Medical Student/Resident Case Reports INTRODUCTION: In the COVID-19 pandemic, pathogenesis and complications of COVID-19 were studied intently. Due to the associated cytokine storm, it is theorized that this triggers a hypercoagulable… read more here.
Keywords: relevant relationships; enoxaparin; covid; web response ... See more keywords
Rivaroxaban versus enoxaparin for the prevention of venous thromboembolism after total knee arthroplasty
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000013465
Abstract: Objective: This article analyzed the clinical efficacy and tolerability of rivaroxaban and enoxaparin in patients undergoing total knee arthroplasty (TKA) surgery. Methods: Five randomized, controlled clinical trials on rivaroxaban versus enoxaparin in patients who underwent… read more here.
Keywords: rivaroxaban versus; enoxaparin; total knee; dvt ... See more keywords
Continuous intravenous infusion of enoxaparin controls thrombin formation more than standard subcutaneous administration in critically ill patients. A sub‐study of the ENOKSI thromboprophylaxis RCT
Sign Up to like & getrecommendations! Published in 2020 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.13697
Abstract: Standard subcutaneous low‐molecular‐weight heparin (LMWH) thromboprophylaxis yields low anti‐factor Xa activity in patients in the intensive care unit (ICU). The aim of the study was to assess coagulation status in ICU patients randomized to receive… read more here.
Keywords: standard subcutaneous; study; enoxaparin; intravenous infusion ... See more keywords
Postoperative fever secondary to enoxaparin usage with pork allergy
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-246904
Abstract: Postoperative fevers are common in hospitalised patients and warrant workup beyond the early post-op period. A 50-year-old man was admitted after sustaining a tibial plateau fracture. Fevers began 3 days after external fixation and persisted through… read more here.
Keywords: postoperative fever; fever secondary; secondary enoxaparin; pork allergy ... See more keywords
Predicting the higher rate of intracranial hemorrhage in glioma patients receiving therapeutic enoxaparin.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-02-767285
Abstract: Venous thromboembolism occurs in up to one-third of patients with primary brain tumors. Spontaneous intracranial hemorrhage (ICH) is also a frequent occurrence in these patients, but there is limited data on the safety of therapeutic… read more here.
Keywords: anticoagulation; glioma; intracranial hemorrhage; patients receiving ... See more keywords
Investigation of the protective effect of enoxaparin and ticagrelor pretreatment against ischemia-reperfusion injury in rat lung tissue.
Sign Up to like & getrecommendations! Published in 2019 at "Revista da Associacao Medica Brasileira"
DOI: 10.1590/1806-9282.65.9.1193
Abstract: OBJECTIVES This study was conducted to reveal the possible protective effects of ticagrelor and enoxaparin pretreatment against ischemia-reperfusion (IR)-induced injury on the lung tissue of a rat model. METHODS Wistar albino rats were randomly divided… read more here.
Keywords: ticagrelor; group; enoxaparin; pretreatment ischemia ... See more keywords