T59 Incorporating Functional Genomic Information To Characterize Polygenic Signal And Identify Variants Enriched For GENE-BY-Environment Interaction For Young Adult Alcohol Problems
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.547
Abstract: Background Polygenic scoring has emerged as one way to characterize aggregate genetic risk; however, the conventional methods for calculating polygenic scores contain a mixture of “true” genetic signal and random noise. We hypothesized that functional… read more here.
Keywords: enriched gene; gene environment; environment interaction;
Impact of 6 month conjugated equine estrogen versus estradiol-treatment on biomarkers and enriched gene sets in healthy mammary tissue of non-human primates
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DOI: 10.1371/journal.pone.0264057
Abstract: Objective To identify distinctly regulated gene markers and enriched gene sets in breast tissue of cynomolgus monkeys (Macaca fascicularis) treated for six months with either conjugated equine estrogens (CEE) or estradiol (E2) by analysis of… read more here.
Keywords: tissue; cee; gene sets; treatment ... See more keywords
Gene expression changes in therapeutic ultrasound-treated venous leg ulcers
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1144182
Abstract: Introduction Low-frequency, low-intensity ultrasound has been previously shown to promote healing of chronic wounds in humans, but mechanisms behind these effects are poorly understood. The purpose of this study was to evaluate gene expression differences… read more here.
Keywords: ultrasound; enriched gene; gene expression; gene ... See more keywords
The Role of a Lung Vascular Endothelium Enriched Gene TMEM100
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DOI: 10.3390/biomedicines11030937
Abstract: Transmembrane protein 100 (TMEM100) is a crucial factor in the development and maintenance of the vascular system. The protein is involved in several processes such as angiogenesis, vascular morphogenesis, and integrity. Furthermore, TMEM100 is a… read more here.
Keywords: role lung; role; lung; enriched gene ... See more keywords