Optimized adaptive enrichment designs for three-arm trials: learning which subpopulations benefit from different treatments.
Sign Up to like & getrecommendations! Published in 2019 at "Biostatistics"
DOI: 10.1093/biostatistics/kxz030
Abstract: We consider the problem of designing a confirmatory randomized trial for comparing two treatments versus a common control in two disjoint subpopulations. The subpopulations could be defined in terms of a biomarker or disease severity… read more here.
Keywords: enrichment designs; design; adaptive enrichment; trial ... See more keywords
Rejoinder to discussion on “Adaptive enrichment designs with a continuous biomarker”
Sign Up to like & getrecommendations! Published in 2022 at "Biometrics"
DOI: 10.1111/biom.13639
Abstract: I am grateful to the editors for inviting a discussion of my article, and to the discussants for their many thoughtful and stimulating comments on the work and suggestions for how it may be extended.… read more here.
Keywords: rejoinder discussion; biomarker; enrichment designs; discussion adaptive ... See more keywords
Development of Innovative Vitamin D Enrichment Designs for Two Typical Italian Fresh Cheeses: Burrata and Giuncata
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031049
Abstract: The aim of this research was to develop innovative cheeses fortified with vitamin D3 (VD3). Formulation studies and analyses of textural properties and chemicals were carried out for these developments. Two traditional Italian varieties of… read more here.
Keywords: designs two; vitamin enrichment; development innovative; two typical ... See more keywords