Chemical Labeling and Enrichment of Histone Glyoxal Adducts.
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DOI: 10.1021/acschembio.1c00864
Abstract: Because of their long half-lives and highly nucleophilic tails, histones are particularly susceptible to accumulating nonenzymatic covalent modifications, such as glycation. The resulting modifications can have profound effects on cellular physiology due to the regulatory… read more here.
Keywords: histone; labeling enrichment; chemistry; enrichment histone ... See more keywords