Albumin Alters the Conformational Ensemble of Amyloid-β by Promiscuous Interactions: Implications for Amyloid Inhibition
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DOI: 10.3389/fmolb.2020.629520
Abstract: Human serum albumin (HSA) is a key endogenous inhibitor of amyloid-β (Αβ) aggregation. In vitro HSA inhibits Aβ fibrillization and targets multiple species along the aggregation pathway including monomers, oligomers, and protofibrils. Amyloid inhibition by… read more here.
Keywords: conformational ensemble; amyloid inhibition; ensemble amyloid; hsa ... See more keywords