Refinement of Peptide Conformational Ensembles by 2D IR Spectroscopy: Application to Ala‒Ala‒Ala.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical journal"
DOI: 10.1016/j.bpj.2018.05.003
Abstract: Characterizing ensembles of intrinsically disordered proteins is experimentally challenging because of the ill-conditioned nature of ensemble determination with limited data and the intrinsic fast dynamics of the conformational ensemble. Amide I two-dimensional infrared (2D IR)… read more here.
Keywords: ala ala; ala; ensemble refinement; conformational ensembles ... See more keywords
Allostery in Coagulation Factor VIIa Revealed by Ensemble Refinement of Crystallographic Structures.
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.03.024
Abstract: A critical step in injury-induced initiation of blood coagulation is the formation of the complex between the trypsin-like protease coagulation factor VIIa (FVIIa) and its cofactor tissue factor (TF), which converts FVIIa from an intrinsically… read more here.
Keywords: coagulation; ensemble refinement; trypsin; crystallographic structures ... See more keywords