Conformational Ensembles of Antibodies Determine Their Hydrophobicity.
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical journal"
DOI: 10.1016/j.bpj.2020.11.010
Abstract: A major challenge in the development of antibody biotherapeutics is their tendency to aggregate. One root cause for aggregation is exposure of hydrophobic surface regions to the solvent. Many current techniques predict the relative aggregation… read more here.
Keywords: hydrophobicity conformational; antibodies determine; determine hydrophobicity; ensembles antibodies ... See more keywords