The Enantiomer of Allopregnanolone Prevents Pressure-Mediated Retinal Degeneration Via Autophagy
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DOI: 10.3389/fphar.2022.855779
Abstract: In an ex vivo rat ocular hypertension (OHT) model, the neurosteroid allopregnanolone (AlloP) exerts neuroprotective effects via enhancement of both GABAA receptors and autophagy. We now examine whether its enantiomer (ent-AlloP), which is largely inactive… read more here.
Keywords: vivo; pressure; allop; allopregnanolone ... See more keywords