A New ent-kaurane Diterpene Glycoside from Seeds of Pharbitis nil
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry of Natural Compounds"
DOI: 10.1007/s10600-017-2024-1
Abstract: A new ent-kaurane diterpene glycoside, pharboside H (1), and three known compounds, benzyl β-D-glucopyranoside (2), 1-(4′-O-glucopyranosyl-4′-hydroxy-3′,5′-dimethoxyphenyl)-2{2′′,6′′-dimethoxy-4′′-[1-(E) propen-3-ol]-phenoxy}-propane-l,3-diol (3), and butyl caffeate (4), were isolated from the seeds of Pharbitis nil. The structure of the new… read more here.
Keywords: new ent; pharbitis nil; kaurane diterpene; ent kaurane ... See more keywords
A New Ent-Kaurane from the Roots of Lasianthaea aurea
Sign Up to like & getrecommendations! Published in 2021 at "Chemistry of Natural Compounds"
DOI: 10.1007/s10600-021-03357-3
Abstract: A known kaurenoic acid (1), together with a new kaurane derivative named 3α-isobutyryloxykaurenoic acid (2), was isolated from the roots of Lasianthaea aurea, a plant endemic to Mexico. The compounds were characterized using their physical… read more here.
Keywords: kaurane roots; roots lasianthaea; new ent; ent kaurane ... See more keywords
Bioactive enmein-type 6,7-seco-ent-kaurane diterpenoids: natural products, synthetic derivatives and apoptosis related mechanism
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-018-1078-3
Abstract: Diterpenoids are important and widely distributed natural compounds with various biological effects, including antitumor, anti-inflammatory and so on. Great efforts have been put in phytochemistry research on diterpenoids. A number of structural modified derivatives and… read more here.
Keywords: seco ent; kaurane diterpenoids; enmein type; type ... See more keywords
Structurally diversified ent-kaurane and abietane diterpenoids from the stems of Tripterygium wilfordii and their anti-inflammatory activity.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105178
Abstract: Four undescribed ent-kaurane diterpenoids, wilkaunoids A - D (1-4), and three undescribed abietane diterpenoids, wilabinoids A - C (13-15), along with thirteen known ones (5-12 and 16-20), were isolated from Tripterygium wilfordii. Their structures were elucidated by extensive spectroscopic… read more here.
Keywords: anti inflammatory; abietane; abietane diterpenoids; ent kaurane ... See more keywords
New ent-kaurane diterpenes with chiral epoxyangelate moieties from Wedelia prostrata
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2018.05.038
Abstract: Abstract Four new ent-kaurane diterpenes with chiral epoxyangelate moieties, (2′R,3′R)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (1), (2′S,3′S)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (2), (2′S,3′R)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (3) and (2′R,3′S)-3α-(2′,3′-epoxyangeloyloxy)-kaur-16-en-19-oic acid (4), along with eight known diterpenes (5−12), were isolated from Wedelia prostrata. The absolute… read more here.
Keywords: chiral epoxyangelate; epoxyangelate moieties; new ent; kaurane diterpenes ... See more keywords
New ent-Kaurane and cleistanthane diterpenoids with potential cytotoxicity from Phyllanthus acidus (L.) Skeels.
Sign Up to like & getrecommendations! Published in 2022 at "Fitoterapia"
DOI: 10.1016/j.fitote.2022.105133
Abstract: Six diterpenoids including three ent-kauranes (1-2, 4) and three cleistanthanes (3, 5-6) were isolated from the roots and stems of Phyllanthus acidus (L.) Skeels. Of them, (16S)-ent-16,17,18-tri-hydroxy-19-nor-kaur-4-en-3-one (1), phyllanthone A (2), and 6-hydroxycleistanthol (3) are… read more here.
Keywords: new ent; phyllanthus acidus; kaurane; acidus skeels ... See more keywords
Discovery of ent-Kaurane Diterpenoids, characteristic metabolites of Isodon species, from an Endophytic fungal strain Geopyxis sp. XY93 inhabiting Isodon parvifolia.
Sign Up to like & getrecommendations! Published in 2022 at "Fitoterapia"
DOI: 10.1016/j.fitote.2022.105160
Abstract: Isogeopyxins A-C (1-3), three new diterpenoids with ent-kaurane, ent-pimarane, and ent-abietane scaffolds, respectively, along with six known ent-kauranoids, were isolated from the fermentation culture of Geopyxis sp. XY93 inhabiting the leaves of Isodon parvifolia. Their… read more here.
Keywords: ent kaurane; geopyxis xy93; characteristic metabolites; isodon parvifolia ... See more keywords
Unusual ent-Kaurane Diterpenes from the Coffea Cultivar S288 Coffee Beans and Molecular Docking to α-Glucosidase.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c06524
Abstract: A total of 11 new (1-11) and 2 known (12 and 13) ent-kaurane diterpene derivatives were identified from the roasted beans of Coffea cultivar S288. Their structures were established by extensive spectroscopic analysis, including one-… read more here.
Keywords: coffea cultivar; molecular docking; cultivar s288; spectroscopy ... See more keywords
New ent-kaurane diterpenoid acids from Nouelia insignis Franch and their anti-inflammatory activity
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra01684b
Abstract: Eleven undescribed ent-kaurane-type diterpenoid acids, namely noueinsiancins A–K (1–11), together with sixteen related known analogs (12–27) were isolated from Nouelia insignis Franch. The chemical structures and absolute configurations of the new compounds were confirmed by… read more here.
Keywords: diterpenoid acids; anti inflammatory; ent kaurane; nouelia insignis ... See more keywords
A new ent-kaurane diterpene from Euphorbia stracheyi Boiss
Sign Up to like & getrecommendations! Published in 2017 at "Natural Product Research"
DOI: 10.1080/14786419.2016.1222385
Abstract: Abstract The chemical investigation of whole plants Euphorbia stracheyi Boiss from China led to the isolation of one new ent-kaurane diterpene, ent-Kaurane-16β,17,19-triol-3-one (1), along with three known ent-kaurane diterpenoids (2–4) as ent-Kaurane-3α,16β,17-triol (2)，ent-16S,17-dihydroxy-kaurane-3-one (3) and… read more here.
Keywords: new ent; stracheyi boiss; kaurane; ent kaurane ... See more keywords
Bioactive Ent-Kaurane Diterpenes Oridonin and Irudonin Prevent Cancer Cells Migration by Interacting with the Actin Cytoskeleton Controller Ezrin
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21197186
Abstract: The ent-kaurane diterpene oridonin was reported to inhibit cell migration and invasion in several experimental models. However, the process by which this molecule exerts its anti-metastatic action has not been yet elucidated. In this article,… read more here.
Keywords: cytoskeleton; ent kaurane; migration; cancer ... See more keywords