Trends in Pricing and Out-of-Pocket Spending on Entecavir Among Commercially Insured Patients, 2014-2018
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.44521
Abstract: This cross-sectional study of health claims from patients with private insurance examines trends in the cost of entecavir prescribed for chronic hepatitis B treatment. read more here.
Keywords: entecavir; pocket spending; entecavir among; pricing pocket ... See more keywords
HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-19602-9
Abstract: Hepatitis B virus (HBV) reverse transcriptase (RT) is essential for viral replication and is an important drug target. Nonetheless, the notorious insolubility of HBV RT has hindered experimental structural studies and structure-based drug design. Here,… read more here.
Keywords: entecavir; hiv; hbv; site ... See more keywords
Editor’s Highlight: Comparative Renal Safety Assessment of the Hepatitis B Drugs, Adefovir, Tenofovir, Telbivudine and Entecavir in Rats
Sign Up to like & getrecommendations! Published in 2017 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfw208
Abstract: The aim of this study was to determine the relative safety of 4 antiviral drugs (telbivudine, tenofovir, adefovir, and entecavir) against hepatitis B virus with respect to kidney function and toxicity in male Sprague Dawley… read more here.
Keywords: entecavir; hepatitis; safety; toxicity ... See more keywords
Compound Biejia-Ruangan tablet as an adjunctive therapy to entecavir for chronic hepatitis B complicated with hepatic fibrosis: A systematic review and meta-analysis of randomized controlled trials
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DOI: 10.1097/md.0000000000030020
Abstract: Background: The compound Biejia-Ruangan tablet (CBRT), as an adjunctive therapy to entecavir, is a potential treatment for hepatic fibrosis (HF) in patients with chronic hepatitis B (HBV). However, the present study yielded inconsistent results. In… read more here.
Keywords: entecavir; cbrt adjunctive; adjunctive therapy; analysis ... See more keywords
Tenofovir may be superior to entecavir for preventing hepatocellular carcinoma and mortality in individuals chronically infected with HBV: a meta-analysis
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DOI: 10.1136/gutjnl-2019-320326
Abstract: Many studies have demonstrated that monotherapy with tenofovir disoproxil fumarate (TDF) or entecavir (ETV) can reduce the risk of liver complications in individuals chronically infected with HBV (CHB). Unclear is whether one monotherapy is more… read more here.
Keywords: hepatocellular carcinoma; entecavir; tenofovir; individuals chronically ... See more keywords
Telbivudine versus entecavir in patients with undetectable hepatitis B virus DNA: a randomized trial
Sign Up to like & getrecommendations! Published in 2017 at "BMC Gastroenterology"
DOI: 10.1186/s12876-017-0572-2
Abstract: BackgroundTelbivudine has been suggested to induce hepatitis B surface antigen (HBsAg) decline to the similar degree as pegylated interferon. We aimed to investigate whether telbivudine could further decrease HBsAg titer in patients who maintain undetectable… read more here.
Keywords: entecavir; trial; dna; hepatitis ... See more keywords
“Black box warning” rash with entecavir - case report
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DOI: 10.1186/s12876-020-01452-3
Abstract: Background Hepatitis B infection is a significant worldwide health issue, predispose to the development of liver cirrhosis and hepatocellular carcinoma. Entecavir is a potent oral antiviral agent of high genetic barrier for the treatment of… read more here.
Keywords: entecavir; hepatitis infection; black box; case ... See more keywords
Is it possible to predict the development of an entecavir resistance mutation in patients with chronic hepatitis B in clinical practice?
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Molecular Hepatology"
DOI: 10.3350/cmh.2017.0069
Abstract: Potent nucleos(t)ide analogs (NAs) with a high genetic barrier, such as entecavir (ETV), tenofovir disoproxil fumarate (TDF), and tenofovir alafenamide fumarate, are strongly recommended as a front-line treatment for chronic hepatitis B (CHB) by current… read more here.
Keywords: entecavir; mutation; hepatitis; resistance ... See more keywords
Multiple drug-resistant HBV mutation may contribute to poor response of adefovir + entecavir in entecavir-resistant patients.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of infection in developing countries"
DOI: 10.3855/jidc.12643
Abstract: INTRODUCTION Adefovir plus entecavir (ADV+ETV) rescue therapy in ETV-resistant patients with chronic hepatitis B virus (HBV) infection is suboptimal in some patients. This study aims to elucidate the evolutionary characteristics of drug-resistant HBV mutants and… read more here.
Keywords: entecavir; etv resistant; hbv; drug ... See more keywords