Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying
Sign Up to like & getrecommendations! Published in 2017 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-017-4820-7
Abstract: Background and AimDiabetes is the main cause of gastroparesis accompanying decreased neuronal nitric oxide synthase (nNOS) in myenteric ganglia of the stomach. Decreased nNOS expression in the stomach also results from defects in apolipoprotein E… read more here.
Keywords: enteric glial; knockout mice; apoe knockout; gastric emptying ... See more keywords
SOX10-Mediated Regulation of Enteric Glial Phenotype in vitro and its Relevance for Neuroinflammatory Disorders
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-025-02321-y
Abstract: The transcription factor SOX10 is a key regulator of myelinated glial cell phenotype and function, with a known role in multiple sclerosis (MS). SOX10 is also expressed in enteric glial cells (EGC) within the gut,… read more here.
Keywords: neuroinflammatory disorders; enteric glial; sox10 target; regulation ... See more keywords
Assessing early postnatal development of the enteric glial network
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733826
Abstract: The enteric glial network is instrumental in intestinal barrier maintenance and repair, but is immature at birth. At birth, enteric glia are restricted to the submucosal and myenteric plexuses, and are driven to populate the… read more here.
Keywords: glial network; enteric glial; physiology; early postnatal ... See more keywords
Cytological, molecular, cytogenetic, and physiological characterization of a novel immortalized human enteric glial cell line
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2023.1170309
Abstract: Enteric glial cells (EGCs), the major components of the enteric nervous system (ENS), are implicated in the maintenance of gut homeostasis, thereby leading to severe pathological conditions when impaired. However, due to technical difficulties associated… read more here.
Keywords: cytological molecular; cell; molecular cytogenetic; cytogenetic physiological ... See more keywords
Enteric glial cell diversification is influenced by spatiotemporal factors and source of neural progenitors in mice
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2024.1392703
Abstract: Previously focused primarily on enteric neurons, studies of the enteric nervous system (ENS) in both health and disease are now broadening to recognize the equally significant role played by enteric glial cells (EGCs). Commensurate to… read more here.
Keywords: glial cell; enteric glial; neural progenitors; cell ... See more keywords
Intestinal Epithelial Barrier Maturation by Enteric Glial Cells Is GDNF-Dependent
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041887
Abstract: Enteric glial cells (EGCs) of the enteric nervous system are critically involved in the maintenance of intestinal epithelial barrier function (IEB). The underlying mechanisms remain undefined. Glial cell line-derived neurotrophic factor (GDNF) contributes to IEB… read more here.
Keywords: intestinal epithelial; barrier; glial cells; gdnf ... See more keywords
Pro-Inflammatory Cytokines Enhanced In Vitro Cytotoxic Activity of Clostridioides difficile Toxin B in Enteric Glial Cells: The Achilles Heel of Clostridioides difficile Infection?
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25020958
Abstract: Bacterial infections are characterized by an inflammatory response, which is essential for infection containment but is also responsible for negative effects on the host. The pathogen itself may have evolved molecular mechanisms to antagonize the… read more here.
Keywords: enteric glial; difficile infection; stimulation; infection ... See more keywords
Gastric Enteric Glial Cells: A New Contributor to the Synucleinopathies in the MPTP-Induced Parkinsonism Mouse
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27217414
Abstract: Accumulating evidence has shown that Parkinson’s disease (PD) is a systemic disease other than a mere central nervous system (CNS) disorder. One of the most important peripheral symptoms is gastrointestinal dysfunction. The enteric nervous system… read more here.
Keywords: mptp induced; enteric glial; gastric enteric; glial cells ... See more keywords