Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.05.034
Abstract: Dietary, microbial, and inflammatory factors modulate the gut-brain axis and influence physiological processes ranging from metabolism to cognition. The gut epithelium is a principal site for detecting such agents, but precisely how it communicates with… read more here.
Keywords: cells gut; gut chemosensors; enterochromaffin cells; chemosensors couple ... See more keywords
Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis.
Sign Up to like & getrecommendations! Published in 2020 at "Immunity"
DOI: 10.1016/j.immuni.2020.10.014
Abstract: The gastrointestinal tract is known as the largest endocrine organ that encounters and integrates various immune stimulations and neuronal responses due to constant environmental challenges. Enterochromaffin (EC) cells, which function as chemosensors on the gut… read more here.
Keywords: interleukin promotes; enterochromaffin cells; intestinal homeostasis; promotes serotonin ... See more keywords
Idiopathic Colitis in Rhesus Macaques Is Associated With Dysbiosis, Abundant Enterochromaffin Cells and Altered T-Cell Cytokine Expression
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary Pathology"
DOI: 10.1177/0300985818780449
Abstract: Idiopathic chronic diarrhea (ICD) is a common ailment affecting captive rhesus macaques (Macaca mulatta). ICD cases are characterized by diarrhea in the absence of commonly identified diarrheal pathogens and multiple recurrences even after supportive therapy.… read more here.
Keywords: rhesus; enterochromaffin cells; colitis; rhesus macaques ... See more keywords
Potential Roles of Enterochromaffin Cells in Early Life Stress-Induced Irritable Bowel Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.837166
Abstract: Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, also known as disorders of the gut–brain interaction; however, the pathophysiology of IBS remains unclear. Early life stress (ELS) is one of… read more here.
Keywords: early life; irritable bowel; enterochromaffin cells; bowel syndrome ... See more keywords
UTP – Gated Signaling Pathways of 5-HT Release from BON Cells as a Model of Human Enterochromaffin Cells
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00429
Abstract: Background: Enterochromaffin cells (EC) synthesize and release 5-HT and ATP to trigger or modulate gut neural reflexes and transmit information about visceral/pain sensation. Alterations in 5-HT signaling mechanisms may contribute to the pathogenesis of IBD… read more here.
Keywords: signaling pathways; atp; enterochromaffin cells; ca2 ... See more keywords
A Focus on Enterochromaffin Cells among the Enteroendocrine Cells: Localization, Morphology, and Role
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073758
Abstract: The intestinal epithelium plays a key role in managing the relationship with the environment, the internal and external inputs, and their changes. One percent of the gut epithelium is represented by the enteroendocrine cells. Among… read more here.
Keywords: enteroendocrine cells; role; morphology; among enteroendocrine ... See more keywords