Enteroendocrine cells in the Echinodermata
Sign Up to like & getrecommendations! Published in 2019 at "Cell and Tissue Research"
DOI: 10.1007/s00441-019-03053-3
Abstract: Enteroendocrine cells are endocrine-like cells found in the luminal epithelia of the digestive tract. These cells have been described in most animal phyla. In echinoderms, the cells have been described mainly in organisms of the… read more here.
Keywords: cells echinodermata; enteroendocrine cells;
Immunohistochemical relationships of huntingtin-associated protein 1 with enteroendocrine cells in the pyloric mucosa of the rat stomach.
Sign Up to like & getrecommendations! Published in 2020 at "Acta histochemica"
DOI: 10.1016/j.acthis.2020.151650
Abstract: Huntingtin-associated protein 1 (HAP1) is a neuronal cytoplasmic protein that is predominantly expressed in the brain and spinal cord. In addition to the central nervous system, HAP1 is also expressed in the peripheral organs including… read more here.
Keywords: protein; associated protein; huntingtin associated; hap1 ... See more keywords
Toll-like receptor 9 expressed in proximal intestinal enteroendocrine cells detects bacteria resulting in secretion of cholecystokinin.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.02.163
Abstract: Toll-like receptors (TLRs) play a key role in the recognition of microbes via detection of specific and conserved microbial molecular features. TLRs, mainly expressed in immune cells, interact with intestinal microbiome. Little is known about… read more here.
Keywords: toll like; secretion; enteroendocrine cells; like receptor ... See more keywords
Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.10.008
Abstract: Glucagon-like peptide 1 (GLP-1) is a hormone released from enteroendocrine L cells. Although first described as a glucoregulatory incretin hormone, GLP-1 also suppresses inflammation and promotes mucosal integrity. Here, we demonstrate that plasma GLP-1 levels… read more here.
Keywords: secretion; glp; enteroendocrine cells; gut barrier ... See more keywords
Effects of active farnesoid X receptor on GLUTag enteroendocrine L cells
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.110923
Abstract: Activated transcription factor (TF) farnesoid X receptor (FXR) represses glucagon-like peptide-1 (GLP-1) secretion in enteroendocrine L cells. This, in turn, reduces insulin secretion, which is triggered when β cells bind GLP-1. Preventing FXR activation could… read more here.
Keywords: secretion; biology; enteroendocrine cells; farnesoid receptor ... See more keywords
Size Effect on Lipid Nanocapsule-Mediated GLP-1 Secretion from Enteroendocrine L Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00742
Abstract: L cells are enteroendocrine cells located throughout the gastrointestinal tract that secrete physiologically important peptides. The most characterized peptides secreted by L cells are the peptide YY (PYY) and the glucagon-like peptides 1 (GLP-1) and… read more here.
Keywords: secretion; effect lipid; size effect; enteroendocrine cells ... See more keywords
Robust differentiation of human enteroendocrine cells from intestinal stem cells
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-021-27901-5
Abstract: Enteroendocrine (EE) cells are the most abundant hormone-producing cells in humans and are critical regulators of energy homeostasis and gastrointestinal function. Challenges in converting human intestinal stem cells (ISCs) into functional EE cells, ex vivo,… read more here.
Keywords: differentiation; intestinal stem; stem cells; enteroendocrine cells ... See more keywords
Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212057119
Abstract: Significance Enteroendocrine cells control key physiological processes such as appetite and insulin secretion through the secretion of neurotransmitters and peptide hormones. The bioactive peptides are subject to complex proteolytic processing essential for their activation or… read more here.
Keywords: enteroendocrine cells; processing; proteases human; mapping prohormone ... See more keywords
Changes in colonic enteroendocrine cells of patients with irritable bowel syndrome following fecal microbiota transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2022.2036809
Abstract: Abstract Objectives The aim was to investigate the effect of fecal microbiota transplantation (FMT) on colonic enteroendocrine cells densities in patients with irritable bowel syndrome (IBS). Materials and methods This study is connected to the… read more here.
Keywords: enteroendocrine cells; fmt; donor fmt; colonic enteroendocrine ... See more keywords
Enteroendocrine Cells: Sensing Gut Microbiota and Regulating Inflammatory Bowel Diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izz217
Abstract: Host sensing in the gut microbiota has been crucial in the regulation of intestinal homeostasis. Although inflammatory bowel diseases (IBDs), multifactorial chronic inflammatory conditions of the gastrointestinal tract, have been associated with intestinal dysbiosis, the… read more here.
Keywords: microbiota; inflammatory bowel; enteroendocrine cells; bowel diseases ... See more keywords
ID2 controls differentiation of enteroendocrine cells in mouse small intestine
Sign Up to like & getrecommendations! Published in 2022 at "Acta Physiologica"
DOI: 10.1111/apha.13773
Abstract: The mammalian gut is the largest endocrine organ. Dozens of hormones secreted by enteroendocrine cells regulate a variety of physiological functions of the gut but also of the pancreas and brain. Here, we examined the… read more here.
Keywords: enteroendocrine cells; controls differentiation; id2 controls; differentiation enteroendocrine ... See more keywords