Non‐polio Enterovirus detection with acute flaccid paralysis: A systematic review
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DOI: 10.1002/jmv.24933
Abstract: Acute flaccid paralysis (AFP), as defined by the World Health Organization (WHO), is characterized by an acute onset of limb weakness. In the post‐polio era, other enterovirus (EV) serotypes associated with AFP may become more… read more here.
Keywords: enterovirus; systematic review; non polio; acute flaccid ... See more keywords
An update on enterovirus 71 infection and interferon type I response
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DOI: 10.1002/rmv.2016
Abstract: Enteroviruses are members of Pichornaviridae family consisting of human enterovirus group A, B, C, and D as well as nonhuman enteroviruses. Hand, foot, and mouth disease (HFMD) is a serious disease which is usually seen… read more here.
Keywords: interferon type; infection interferon; enterovirus; update enterovirus ... See more keywords
Does enterovirus 71 urge for effective vaccine control strategies? Challenges and current opinion
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DOI: 10.1002/rmv.2322
Abstract: Enterovirus 71 (EV71) is an infectious virus affecting all age groups of people around the world. It is one of the major aetiologic agents for HFMD (hand, foot and mouth disease) identified globally. It has… read more here.
Keywords: enterovirus; effective vaccine; urge effective; enterovirus urge ... See more keywords
Identification and production of mouse scFv to specific epitope of enterovirus-71 virion protein-2 (VP2)
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DOI: 10.1007/s00705-018-3731-z
Abstract: Enterovirus-71 (EV71) and coxsackievirus-A16 (CA16) frequently cause hand-foot-mouth disease (HFMD) epidemics among infants and young children. CA16 infections are usually mild, while EV71 disease may be fatal due to neurologic complications. As such, the ability… read more here.
Keywords: ev71; protein vp2; protein; enterovirus ... See more keywords
Development and evaluation of a rapid recombinase polymerase amplification assay for the detection of human enterovirus 71
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DOI: 10.1007/s00705-018-3859-x
Abstract: Enterovirus 71 (EV71) is one of the most common pathogens of hand, foot, and mouth disease (HFMD). A rapid reverse transcription recombinase polymerase amplification (RT-RPA) assay was established to detect EV71 subgenotype C4 (EV71-C4). The… read more here.
Keywords: recombinase polymerase; detection; enterovirus; polymerase amplification ... See more keywords
Process optimization for the rapid production of Enterovirus 71
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DOI: 10.1007/s10616-019-00340-3
Abstract: Enterovirus 71 (EV71) infection can cause hand–foot-and-mouth disease (HFMD). Inactivated EV71 vaccine was effective to prevent EV71 derived HFMD. A highly efficient and economical process for producing EV71 is needed. In our study, the epidemic… read more here.
Keywords: ev71; production; enterovirus; optimization rapid ... See more keywords
Evaluación de una técnica de diagnóstico molecular Xpert EV (Cepheid ® ) en la meningitis por enterovirus
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DOI: 10.1016/j.anpedi.2016.09.010
Abstract: Resumen Introduccion Las tecnicas de biologia molecular han demostrado ser utiles en la deteccion del enterovirus en ninos con meningitis aseptica. El objetivo de nuestro estudio fue analizar cambios en la practica clinica tras la… read more here.
Keywords: meningitis; por; xpert cepheid; enterovirus ... See more keywords
Establishment of Asia-Pacific Network for Enterovirus Surveillance.
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DOI: 10.1016/j.vaccine.2019.09.111
Abstract: Enteroviruses (EV), the major pathogens of hand, foot, and mouth disease (HFMD) and herpangina, affect millions of children each year. Most human enteroviruses cause self-limited infections except polioviruses, enterovirus A71 (EV-A71), enterovirus D68 (EV-D68), and… read more here.
Keywords: asia pacific; enterovirus surveillance; enterovirus; network enterovirus ... See more keywords
VP1 residues around the five-fold axis of enterovirus A71 mediate heparan sulfate interaction.
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DOI: 10.1016/j.virol.2016.11.009
Abstract: Enterovirus A71 (EV-A71) is a neurotropic enterovirus that uses heparan sulfate as an attachment receptor. The molecular determinants of EV-A71-heparan sulfate interaction are unknown. With In silico heparin docking and mutagenesis of all possible lysine… read more here.
Keywords: heparin; enterovirus; heparan sulfate; interaction ... See more keywords
Involvement of VCP/UFD1/Nucleolin in the viral entry of Enterovirus A species
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DOI: 10.1016/j.virusres.2020.197974
Abstract: Abstract Valosin-containing protein (VCP) plays roles in various cellular activities. Recently, Enterovirus A71 (EVA71) infection was found to hijack the VCP protein. However, the mechanism by which VCP participates in the EVA71 life cycle remains… read more here.
Keywords: enterovirus; infection; vcp ufd1; vcp ... See more keywords
A SCAFFOLD SIMPLIFICATION STRATEGY LEADS TO A NOVEL GENERATION OF DUAL HUMAN IMMUNODEFICIENCY VIRUS AND ENTEROVIRUS-A71 ENTRY INHIBITORS.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b01737
Abstract: Currently there are only three FDA-approved drugs that inhibit HIV entry-fusion into host cells. The situation is even worse for enterovirus EV71 infection for which no antiviral therapies are available. We describe here the discovery… read more here.
Keywords: enterovirus; chemistry; simplification strategy; scaffold simplification ... See more keywords