Articles with "enthesis" as a keyword



Revealing the Auxetic Behavior of Biomimetic Multimaterial and Region‐Specific Nanofibrous Fascicle‐Inspired Scaffolds via Synchrotron Multiscale Digital Volume Correlation: Innovative Building Blocks for the Enthesis Regeneration

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Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202511660

Abstract: Enthesis lesions are one of the prevalent causes of injuries in the tendon tissue. The gradient of mineralization, extracellular matrix organization and auxetic mechanical properties, make enthesis regeneration challenging. Innovative electrospun fascicle‐inspired nanofibrous poly(L‐lactic)acid/collagen type… read more here.

Keywords: enthesis regeneration; synchrotron; enthesis; behavior ... See more keywords

Bone‐Adhesive Anisotropic Tough Hydrogel Mimicking Tendon Enthesis

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Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202206207

Abstract: Tendon consists of soft collagen, yet it is mechanically strong and firmly adhered to the bone owing to its hierarchically anisotropic structure and unique tendon‐to‐bone integration (enthesis), respectively. Despite the recent advances in biomaterials, hydrogels… read more here.

Keywords: hydrogel; bone; bone adhesive; enthesis ... See more keywords
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Cytokine‐Induced and Stretch‐Induced Sphingosine 1‐Phosphate Production by Enthesis Cells Could Favor Abnormal Ossification in Spondyloarthritis

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Published in 2019 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3844

Abstract: Spondyloarthritis (SpA) is a common rheumatic disease characterized by enthesis inflammation (enthesitis) and ectopic ossification (enthesophytes). The current pathogenesis model suggests that inflammation and mechanical stress are both strongly involved in SpA pathophysiology. We have… read more here.

Keywords: spondyloarthritis; abnormal ossification; enthesis; ossification ... See more keywords

Electrohydrodynamic-Printed Dual-Triphase Microfibrous Scaffolds Reshaping the Lipidomic Profile for Enthesis Healing in a Rat Rotator Cuff Repair Model.

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Published in 2024 at "Small"

DOI: 10.1002/smll.202406069

Abstract: Rotator cuff injuries often result in chronic pain and functional limitations due to retears and scar formation at the enthesis. This study assess the efficacy of electrohydrodynamic-printed microfibrous dual-triphase scaffolds (DTSs), designed to optimize enthesis… read more here.

Keywords: electrohydrodynamic printed; rotator cuff; repair; enthesis ... See more keywords

Dynamic Deformation Behavior of the Porcine Anterior Cruciate Ligament Enthesis Under Anterior Tibial Loading

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Published in 2024 at "Annals of Biomedical Engineering"

DOI: 10.1007/s10439-024-03654-2

Abstract: This study determined the insertion angle at the porcine anterior cruciate ligament (ACL) enthesis under joint loading to provide information on the structure and mechanical function of the enthesis. Ten intact porcine knee joints were… read more here.

Keywords: anterior cruciate; porcine anterior; cruciate ligament; ligament ... See more keywords

Heparin functionalization increases retention of TGF-β2 and GDF5 on biphasic silk fibroin scaffolds for tendon/ligament-to-bone tissue engineering.

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Published in 2018 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2018.03.017

Abstract: The tendon/ligament-to-bone transition (enthesis) is a highly specialized interphase tissue with structural gradients of extracellular matrix composition, collagen molecule alignment and mineralization. These structural features are essential for enthesis function, but are often not regenerated… read more here.

Keywords: ligament bone; enthesis; tissue; bone ... See more keywords

Assembly, maturation, and degradation of the supraspinatus enthesis.

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Published in 2018 at "Journal of shoulder and elbow surgery"

DOI: 10.1016/j.jse.2017.10.030

Abstract: The development of the rotator cuff enthesis is still poorly understood. The processes in the early and late developmental steps are gradually elucidated, but it is still unclear how cell activities are coordinated during development… read more here.

Keywords: maturation; supraspinatus enthesis; degradation supraspinatus; enthesis ... See more keywords

Ultrasonography of enthesis in psoriatic arthritis: a descriptive and reliability analysis of elemental lesions and power Doppler subtypes

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Published in 2019 at "Scandinavian Journal of Rheumatology"

DOI: 10.1080/03009742.2019.1602881

Abstract: Objective: To evaluate the reliability and prevalence of enthesis ultrasound (US) elemental lesions in patients with psoriatic arthritis (PsA), using the Madrid Sonographic Enthesis Index (MASEI) and Outcome Measures in Rheumatology (OMERACT) definitions. Methods: The… read more here.

Keywords: psoriatic arthritis; enthesis; doppler; elemental lesions ... See more keywords

Regulation of entheseal IL-23 expression by IL-4 and IL-13 as an explanation for arthropathy development under dupilumab therapy.

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Published in 2020 at "Rheumatology"

DOI: 10.1093/rheumatology/keaa568

Abstract: OBJECTIVES Dupilumab blocks the IL-4 receptor (IL-4R) and thus signalling of the 'Th2' cytokines IL-4 and IL-13. It has a license to treat atopic eczema and was recently linked to emergent enthesitis and psoriasis. We… read more here.

Keywords: explanation; enthesis; entheseal; expression ... See more keywords

Entheseal involvement in patients with systemic lupus erythematosus: an ultrasound study

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Published in 2018 at "Rheumatology"

DOI: 10.1093/rheumatology/key189

Abstract: Objectives The main objective of this study is to explore the prevalence and distribution of entheseal US changes in a cohort of SLE patients, taking as controls a group including both PsA patients and healthy… read more here.

Keywords: enthesis; entheseal involvement; study; sle patients ... See more keywords

Enthesopathy and involvement of synovio-entheseal complex in systemic sclerosis: an ultrasound pilot study.

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Published in 2019 at "Rheumatology"

DOI: 10.1093/rheumatology/kez322

Abstract: OBJECTIVES SSc is a chronic autoimmune disease characterized by inflammation of the skin and multiple internal organs. Articular involvement is one of the main features of SSc, and typical hallmarks of SpA have been found… read more here.

Keywords: ssc patients; enthesis; synovio entheseal; study ... See more keywords