Role of the IL-23 pathway in the pathogenesis and treatment of enthesitis in psoriatic arthritis
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2020.1737855
Abstract: ABSTRACT Introduction Enthesitis is a key feature of spondyloarthritis (SpA). Several studies have underlined the role of interleukin (IL)-23 in SpA development as a crucial cytokine in the pathogenesis of enthesitis. Area covered This review… read more here.
Keywords: enthesitis; role pathway; treatment enthesitis; pathway pathogenesis ... See more keywords
Resolution of Enthesitis by Guselkumab and Relationships to Disease Burden: 1-Year Results of Two Phase-3 Psoriatic Arthritis Studies.
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology"
DOI: 10.1093/rheumatology/keab285
Abstract: OBJECTIVE To further characterize the effect of guselkumab, a selective interleukin-23p19-subunit inhibitor approved for psoriatic arthritis (PsA), on enthesitis and assess relationships between enthesitis resolution and patient status/outcomes. METHODS Adults with active PsA despite standard… read more here.
Keywords: psoriatic arthritis; resolution; enthesitis; disease ... See more keywords
Controversies in rheumatology: Imaging of enthesitis in spondyloarthritis - does it mean anything for treatment decisions?
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac116
Abstract: Enthesitis is considered a hallmark manifestation of spondyloarthritis including axial spondyloarthritis and psoriatic arthritis. Detection of enthesitis might be challenging in both diagnostic and classification processes. In this debate, we discuss the controversy on the… read more here.
Keywords: treatment decisions; rheumatology; spondyloarthritis; controversies rheumatology ... See more keywords
Prevalence and clinical associations of ultrasound-confirmed enthesitis in systemic lupus erythematosus.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead123
Abstract: OBJECTIVES To assess the prevalence of ultrasound (US)-confirmed enthesitis in a cohort of patients with systemic lupus erythematosus (SLE) and to analyze the clinical associations to enthesitis during the course of SLE. METHODS In a… read more here.
Keywords: sle; confirmed enthesitis; ultrasound confirmed; systemic lupus ... See more keywords
Enthesitis in patients with psoriatic arthritis treated with secukinumab or adalimumab: a post hoc analysis of the EXCEED study.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead181
Abstract: OBJECTIVES To evaluate enthesitis treatment response, including time to resolution and data from multiple enthesitis instruments, in patients with psoriatic arthritis (PsA) treated with secukinumab or adalimumab for 52 weeks. METHODS In this post hoc analysis… read more here.
Keywords: lei sparcc; secukinumab adalimumab; resolution; adalimumab ... See more keywords
The association between sonographic enthesitis with sonographic synovitis and tenosynovitis in psoriatic arthritis patients.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead202
Abstract: OBJECTIVES To examine the association between sonographic enthesitis with sonographic synovitis and tenosynovitis in psoriatic arthritis (PsA) patients, and the association between sonographic enthesitis and clinical characteristics. METHODS Consecutive PsA patients that fulfilled the classification… read more here.
Keywords: enthesitis sonographic; association sonographic; sonographic synovitis; sonographic enthesitis ... See more keywords
The management of enthesitis in clinical practice.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000715
Abstract: PURPOSE OF REVIEW Enthesitis is a hallmark feature of the spondyloarthropathies (SpA). This review provides an overview of recent insights on diagnosis and management of enthesitis. RECENT FINDINGS Recent studies support the use of imaging… read more here.
Keywords: clinical practice; management enthesitis; head; enthesitis clinical ... See more keywords
Enthesitis in patients with psoriatic arthritis: A nationwide data from the Chinese Registry of Psoriatic Arthritis (CREPAR)
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002646
Abstract: Abstract Background: The clinical features of enthesitis in patients with psoriatic arthritis (PsA) have been reported in some Western countries, but data in China are very limited. This study aimed to describe the characteristics of… read more here.
Keywords: patients psoriatic; psoriatic arthritis; enthesitis patients; chinese registry ... See more keywords
The use of ultrasound to detect enthesitis as a potential guide for intervention in patients with psoriasis at risk of psoriatic arthritis: a systematic review.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of dermatology"
DOI: 10.1111/ijd.16645
Abstract: INTRODUCTION Psoriatic arthritis is estimated to develop in 2% of patients with psoriasis per year and can result in significant morbidity. Early diagnosis and treatment of psoriatic arthritis are imperative to prevent irreversible arthritic joint… read more here.
Keywords: patients psoriasis; psoriatic arthritis; arthritis; risk ... See more keywords
SAT0482 Subclinical enthesopathy in psoriatic patients and its relation to other disease parameters: an ultrasound study
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.1595
Abstract: Background Psoriasis is a chronic immune-mediated inflammatory skin disease characterized by reddish, thick patches covered with marked silvery scaling [1]. In about 70% of the patients, psoriasis is present many years before the onset of… read more here.
Keywords: psoriatic arthritis; enthesitis; psoriasis; arthritis ... See more keywords
SAT0448 Apremilast treatment and long-term (up to 156 weeks) improvements in dactylitis and enthesitis in patients with psoriatic arthritis: analysis of a large database of the phase iii clinical development program
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.3821
Abstract: Background Dactylitis and enthesitis, hallmark features of psoriatic arthritis (PsA), may be difficult to manage. PALACE 1, 2, and 3 compared the efficacy and safety of apremilast (APR) with placebo (PBO) in patients (pts) with… read more here.
Keywords: enthesitis; pfizer; dactylitis; celgene corporation ... See more keywords